Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 68 0.343 0.885 1.00 0.600 None 0.967 1 0 2005 2019
Entrez Id: 4194
Gene Symbol: MDM4
MDM4 		O15151 MDM4 regulator of p53 Nucleic acid binding 20 0.461 0.808 1.00 0.600 None 1.000 1 0 2002 2018
Entrez Id: 5747
Gene Symbol: PTK2
PTK2 		Q05397 protein tyrosine kinase 2 Kinase 16 0.497 0.808 1.00 0.550 None 1.000 1 0 2003 2019
Entrez Id: 6046
Gene Symbol: BRD2
BRD2 		P25440 bromodomain containing 2 Epigenetic regulator 10 0.450 0.808 1.00 0.530 None 1.000 1 0 1999 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.500 None 0.973 3 3 1988 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 0.941 0 0 2000 2020
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 45 0.424 0.808 2.6E-12 0.500 None 0.977 0 0 2008 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.430 None 1.000 1 0 1995 2019
Entrez Id: 8842
Gene Symbol: PROM1
PROM1 		O43490 prominin 1 Transporter 23 0.410 0.846 1.9E-22 0.400 None 0.982 3 0 2006 2020
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		P16455 O-6-methylguanine-DNA methyltransferase 26 0.412 0.885 1.2E-07 0.400 None 0.974 2 0 1992 2020
Entrez Id: 3020
Gene Symbol: H3-3A
H3-3A 		P84243 H3.3 histone A 8 0.559 0.692 0.12 0.400 None 0.933 2 0 2012 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 1.000 1 0 1996 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 1.000 1 0 1986 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 78 0.369 0.885 1.00 0.400 None 0.952 1 0 2007 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1 		P02751 fibronectin 1 Signaling 44 0.365 0.962 1.4E-03 0.400 None 1.000 1 0 1991 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 89 0.327 0.923 0.98 0.400 None 1.000 1 0 2000 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 98 0.333 0.923 0.84 0.400 None 0.958 1 0 1999 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 109 0.310 0.962 2.7E-04 0.400 None 1.000 1 0 1991 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 1.000 1 0 1991 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 45 0.357 0.923 8.5E-17 0.400 None 0.986 1 0 1988 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 167 0.266 0.923 2.4E-05 0.400 None 0.994 1 0 1992 2020
Entrez Id: 7158
Gene Symbol: TP53BP1
TP53BP1 		Q12888 tumor protein p53 binding protein 1 Epigenetic regulator 14 0.520 0.731 1.00 0.400 None 1.000 1 0 2010 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.400 None 0.978 1 0 1993 2020
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		P50591 TNF superfamily member 10 Signaling 49 0.413 0.885 0.13 0.400 None 0.963 1 0 2007 2019
Entrez Id: 1508
Gene Symbol: CTSB
CTSB 		P07858 cathepsin B Enzyme 17 0.457 0.846 5.9E-11 0.400 None 1.000 1 0 1995 2019