Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 73 0.401 0.808 0.15 0.800 definitive 0.972 15 109 1990 2020
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.500 None 0 0
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.400 None 1.000 2 1 2000 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.360 None 1.000 2 0 2001 2017
Entrez Id: 1495
Gene Symbol: CTNNA1
CTNNA1 		P35221 catenin alpha 1 Cellular structure 16 0.584 0.538 0.97 0.340 None 0.833 3 0 2013 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.320 None 1.000 0 0 2001 2011
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 19 0.521 0.769 1.3E-18 0.320 None 1.000 0 0 2004 2006
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.310 None 1.000 3 0 2005 2012
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.310 None 1.000 2 0 2006 2017
Entrez Id: 9064
Gene Symbol: MAP3K6
MAP3K6 		O95382 mitogen-activated protein kinase kinase kinase 6 Kinase 3 0.861 0.192 1.1E-16 0.310 None 1.000 1 0 2014 2014
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.310 None 1.000 1 0 2000 2011
Entrez Id: 7298
Gene Symbol: TYMS
TYMS 		P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.300 None 1.000 4 0 2005 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.300 None 1.000 4 0 1999 2012
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.300 None 1.000 4 0 2000 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.300 None 1.000 3 0 2004 2011
Entrez Id: 374
Gene Symbol: AREG
AREG 		P15514 amphiregulin Signaling 32 0.487 0.769 0.35 0.300 None 1.000 3 0 2005 2006
Entrez Id: 1806
Gene Symbol: DPYD
DPYD 		Q12882 dihydropyrimidine dehydrogenase Enzyme 45 0.493 0.846 3.4E-22 0.300 None 1.000 3 0 2005 2008
Entrez Id: 7372
Gene Symbol: UMPS
UMPS 		P11172 uridine monophosphate synthetase 31 0.584 0.615 1.1E-04 0.300 None 1.000 3 0 2006 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.300 None 1.000 3 0 2004 2012
Entrez Id: 387
Gene Symbol: RHOA
RHOA 		P61586 ras homolog family member A Enzyme modulator 46 0.502 0.808 0.60 0.300 None 1.000 3 0 2004 2014
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A 		O14497 AT-rich interaction domain 1A 48 0.455 0.846 1.00 0.300 None 1.000 3 0 2011 2014
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.300 None 1.000 2 0 2011 2012
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		P26358 DNA methyltransferase 1 Epigenetic regulator 57 0.406 0.885 1.00 0.300 None 1.000 2 0 2007 2011
Entrez Id: 8000
Gene Symbol: PSCA
PSCA 		O43653 prostate stem cell antigen 13 0.555 0.615 0.17 0.300 None 1.000 2 0 2008 2015
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6 		P11509 cytochrome P450 family 2 subfamily A member 6 44 0.556 0.731 5.4E-09 0.300 None 1.000 2 0 2002 2011