| Gene | UniProt | Gene Full Name | Protein Class | N. diseases g | DSI g | DPI g | pLI | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
P35555 | fibrillin 1 | Calcium-binding protein | 552 | 0.417 | 0.846 | 1.00 | 0.040 | None | 1.000 | 4 | 1 | 1995 | 2014 | ||||
|
P01019 | angiotensinogen | Enzyme modulator | 765 | 0.367 | 0.923 | 5.0E-08 | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||
|
O75173 | ADAM metallopeptidase with thrombospondin type 1 motif 4 | Enzyme | 84 | 0.582 | 0.692 | 2.0E-06 | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||
|
P37173 | transforming growth factor beta receptor 2 | Kinase | 502 | 0.413 | 0.846 | 0.13 | 0.010 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||
|
P10600 | transforming growth factor beta 3 | Signaling | 230 | 0.498 | 0.808 | 0.99 | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||
|
P60709 | actin beta | Cellular structure | 1110 | 0.325 | 0.923 | 0.99 | 0.010 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||
|
Q15746 | myosin light chain kinase | Kinase | 199 | 0.510 | 0.846 | 9.2E-12 | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||
|
P39900 | matrix metallopeptidase 12 | Enzyme | 216 | 0.484 | 0.885 | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | |||||
|
Q13485 | SMAD family member 4 | Transcription factor | 575 | 0.401 | 0.808 | 1.00 | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||
|
microRNA 21 | 726 | 0.363 | 0.846 | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | |||||||
|
P28300 | lysyl oxidase | 328 | 0.447 | 0.846 | 0.99 | 0.010 | None | 1.000 | 1 | 0 | 2016 | 2016 | |||||
|
Q14469 | hes family bHLH transcription factor 1 | Transcription factor | 243 | 0.468 | 0.885 | 0.71 | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||
|
P01133 | epidermal growth factor | 774 | 0.357 | 0.923 | 8.5E-17 | 0.010 | None | 1.000 | 1 | 0 | 1995 | 1995 | |||||
|
O15072 | ADAM metallopeptidase with thrombospondin type 1 motif 3 | Enzyme | 116 | 0.581 | 0.808 | 1.0E-10 | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 |