Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R 		P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.700 strong 0.977 43 4 2001 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.100 None 0.955 22 0 2004 2019
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		P01344 insulin like growth factor 2 604 0.390 0.885 4.4E-02 0.090 None 0.889 9 0 2013 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.060 None 0.833 6 0 2014 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.050 None 1.000 5 0 2011 2017
Entrez Id: 3643
Gene Symbol: INSR
INSR 		P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.030 None 1.000 3 0 2017 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.030 None 0.667 3 0 2017 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.030 None 0.667 3 0 2017 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.030 None 0.667 3 0 2017 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.030 None 0.667 3 0 2017 2019
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3 		P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.020 None 1.000 2 0 2009 2014
Entrez Id: 374
Gene Symbol: AREG
AREG 		P15514 amphiregulin Signaling 221 0.487 0.769 0.35 0.020 None 1.000 2 0 2011 2017
Entrez Id: 8660
Gene Symbol: IRS2
IRS2 		Q9Y4H2 insulin receptor substrate 2 152 0.535 0.654 0.99 0.020 None 1.000 2 0 2008 2010
Entrez Id: 7430
Gene Symbol: EZR
EZR 		P15311 ezrin Cellular structure 255 0.476 0.808 0.18 0.020 None 1.000 2 0 2014 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.020 None 1.000 2 0 2014 2017
Entrez Id: 156
Gene Symbol: GRK2
GRK2 		P25098 G protein-coupled receptor kinase 2 Kinase 159 0.532 0.654 1.00 0.020 None 1.000 2 0 2016 2017
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1 		P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 285 0.477 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 84152
Gene Symbol: PPP1R1B
PPP1R1B 		Q9UD71 protein phosphatase 1 regulatory inhibitor subunit 1B Enzyme modulator 82 0.617 0.500 0.24 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8503
Gene Symbol: PIK3R3
PIK3R3 		Q92569 phosphoinositide-3-kinase regulatory subunit 3 Enzyme modulator 101 0.556 0.692 3.4E-10 0.010 None 1.000 1 0 2016 2016
Entrez Id: 57626
Gene Symbol: KLHL1
KLHL1 		Q9NR64 kelch like family member 1 100 0.569 0.654 7.2E-07 0.010 None 1.000 1 0 2017 2017
Entrez Id: 51573
Gene Symbol: GDE1
GDE1 		Q9NZC3 glycerophosphodiester phosphodiesterase 1 228 0.481 0.808 6.1E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 64599
Gene Symbol: GIGYF1
GIGYF1 		O75420 GRB10 interacting GYF protein 1 15 0.751 0.269 3.4E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 57167
Gene Symbol: SALL4
SALL4 		Q9UJQ4 spalt like transcription factor 4 Transcription factor 245 0.489 0.769 1.00 0.010 None 1.000 1 0 2016 2016