Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.500 None 1.000 3 0 1996 2008
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.400 None 1.000 1 0 2008 2008
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.300 None 1.000 8 0 1986 2018
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 441 0.431 0.885 3.5E-02 0.300 None 1.000 2 0 1986 2008
Entrez Id: 8660
Gene Symbol: IRS2
IRS2
Q9Y4H2 insulin receptor substrate 2 152 0.535 0.654 0.99 0.300 None 1.000 2 0 2010 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.300 None 1.000 2 0 2009 2011
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM
P11215 integrin subunit alpha M 343 0.443 0.808 3.3E-11 0.300 None 1.000 1 0 2018 2018
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.300 None 1.000 1 0 2001 2001
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 597 0.401 0.846 1.00 0.300 None 1.000 1 0 2018 2018
Entrez Id: 9332
Gene Symbol: CD163
CD163
Q86VB7 CD163 molecule Enzyme 369 0.427 0.846 8.3E-04 0.300 None 1.000 1 0 2018 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.300 None 1.000 1 0 2018 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.300 None 1.000 1 0 2003 2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.300 None 1.000 1 0 2018 2018
Entrez Id: 6492
Gene Symbol: SIM1
SIM1
P81133 SIM bHLH transcription factor 1 Transcription factor 84 0.626 0.654 1.00 0.300 None 1.000 1 0 2008 2008
Entrez Id: 6667
Gene Symbol: SP1
SP1
P08047 Sp1 transcription factor Nucleic acid binding 209 0.493 0.769 1.00 0.300 None 1.000 1 0 2001 2001
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 292 0.478 0.846 0.96 0.300 None 1.000 1 0 2018 2018
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
P05771 protein kinase C beta Kinase 317 0.453 0.885 1.00 0.300 None 1.000 1 0 2007 2007
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 528 0.396 0.846 0.85 0.300 None 1.000 1 0 2018 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.300 None 1.000 1 0 2018 2018
Entrez Id: 10549
Gene Symbol: PRDX4
PRDX4
Q13162 peroxiredoxin 4 Enzyme 59 0.619 0.692 2.7E-02 0.300 None 1.000 1 0 2010 2010
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 301 0.477 0.808 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.300 None 1.000 1 0 2013 2013
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.300 None 1.000 1 0 2013 2013
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.300 None 1.000 1 0 2010 2010