Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5648
Gene Symbol: MASP1
MASP1 		P48740 mannan binding lectin serine peptidase 1 Enzyme 123 0.565 0.885 1.2E-11 0.100 None 1.000 1 1 2014 2014
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1 		Q07817 BCL2 like 1 Signaling 212 0.493 0.885 0.94 0.300 None 1.000 1 0 2002 2002
Entrez Id: 79068
Gene Symbol: FTO
FTO 		Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 286 0.486 0.885 8.4E-08 0.010 None 1.000 1 0 2017 2017
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.300 None 1.000 1 0 2002 2002
Entrez Id: 2521
Gene Symbol: FUS
FUS 		P35637 FUS RNA binding protein Nucleic acid binding 301 0.470 0.846 1.00 0.100 None 1.000 16 0 2010 2017
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS 		P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.090 None 1.000 9 1 1997 2018
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.030 None 1.000 3 2 2011 2014
Entrez Id: 1509
Gene Symbol: CTSD
CTSD 		P07339 cathepsin D Enzyme 242 0.478 0.846 9.2E-04 0.310 None 1.000 2 0 2002 2019
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 317 0.455 0.846 1.00 0.110 None 1.000 2 1 2014 2017
Entrez Id: 29110
Gene Symbol: TBK1
TBK1 		Q9UHD2 TANK binding kinase 1 Kinase 207 0.513 0.846 7.5E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 12
Gene Symbol: SERPINA3
SERPINA3 		P01011 serpin family A member 3 Enzyme modulator 229 0.486 0.846 8.8E-14 0.200 None 1.000 1 0 2002 2002
Entrez Id: 2896
Gene Symbol: GRN
GRN 		P28799 granulin precursor 412 0.435 0.846 7.0E-02 0.010 None 1.000 1 0 2014 2014
Entrez Id: 2936
Gene Symbol: GSR
GSR 		P00390 glutathione-disulfide reductase Enzyme 206 0.494 0.846 1.3E-06 0.010 None 1.000 1 0 2006 2006
Entrez Id: 328
Gene Symbol: APEX1
APEX1 		P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 305 0.458 0.846 1.9E-07 0.010 None 1.000 1 1 2010 2010
Entrez Id: 7431
Gene Symbol: VIM
VIM 		P08670 vimentin 644 0.372 0.846 0.71 0.300 None 1.000 1 0 2002 2002
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.100 None 1.000 38 0 2007 2020
Entrez Id: 10133
Gene Symbol: OPTN
OPTN 		Q96CV9 optineurin 136 0.548 0.808 5.9E-18 0.090 None 1.000 9 0 2011 2019
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4 		P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 248 0.492 0.808 8.5E-05 0.020 None 1.000 2 0 2009 2012
Entrez Id: 1471
Gene Symbol: CST3
CST3 		P01034 cystatin C 370 0.436 0.808 3.9E-03 0.310 None 1.000 2 0 2002 2017
Entrez Id: 5445
Gene Symbol: PON2
PON2 		Q15165 paraoxonase 2 117 0.566 0.808 5.4E-05 0.020 None 1.000 2 1 2010 2012
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		Q99700 ataxin 2 Nucleic acid binding 341 0.482 0.808 0.85 0.020 None 0.500 2 0 2011 2019
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP 		Q92793 CREB binding protein 438 0.428 0.808 1.00 0.300 None 1.000 1 0 2002 2002
Entrez Id: 26503
Gene Symbol: SLC17A5
SLC17A5 		Q9NRA2 solute carrier family 17 member 5 Transporter 252 0.491 0.808 6.9E-10 0.010 None 1.000 1 0 2017 2017
Entrez Id: 331
Gene Symbol: XIAP
XIAP 		P98170 X-linked inhibitor of apoptosis Enzyme modulator 321 0.447 0.808 0.92 0.300 None 1.000 1 0 2002 2002