Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.010 None 1.000 1 0 2013 2013
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.100 None 0 0
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.150 None 1.000 5 3 2002 2015
Entrez Id: 790
Gene Symbol: CAD
CAD
P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 249 0.482 0.846 1.00 0.050 None 0.800 5 0 2009 2019
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 224 0.502 0.846 9.9E-07 0.010 None 1.000 1 2 2007 2007
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.010 None 1.000 1 0 2014 2014
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5319
Gene Symbol: PLA2G1B
PLA2G1B
P04054 phospholipase A2 group IB Enzyme 268 0.468 0.846 1.0E-10 0.010 None 1.000 1 0 1998 1998
Entrez Id: 8398
Gene Symbol: PLA2G6
PLA2G6
O60733 phospholipase A2 group VI Enzyme modulator 350 0.476 0.846 2.5E-10 0.010 None 1.000 1 0 1998 1998
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.200 None 1.000 11 0 1992 2016
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.080 None 1.000 8 0 1986 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.050 None 0.800 5 1 1997 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.050 None 1.000 5 1 2005 2017
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
P07996 thrombospondin 1 480 0.407 0.885 1.00 0.030 None 1.000 3 1 2002 2004
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 412 0.426 0.885 7.8E-05 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.010 None 1.000 1 0 2005 2005
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.010 None 1.000 1 1 2007 2007
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.010 None 1.000 1 0 2003 2003
Entrez Id: 875
Gene Symbol: CBS
CBS
P0DN79 P35520 cystathionine beta-synthase Enzyme 295 0.465 0.885 3.1E-05 0.010 None 1.000 1 0 1996 1996
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.010 None 1.000 1 1 2017 2017
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.100 None 0 0
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2015 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 0 1998 1998
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.010 None 1.000 1 2 2007 2007