Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.400 None 1.000 1 0 1991 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.400 None 1.000 1 0 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.400 None 0.978 1 0 1999 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 84 0.344 0.885 1.3E-05 0.400 None 0.964 1 0 1992 2018
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		O60674 Janus kinase 2 Kinase 53 0.385 0.885 0.65 0.400 None 1.000 0 0 1997 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.320 None 1.000 1 0 2006 2011
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		Q03164 lysine methyltransferase 2A 46 0.410 0.885 1.00 0.400 None 0.979 2 0 1994 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1 		P18887 X-ray repair cross complementing 1 23 0.421 0.923 6.3E-09 0.310 None 1.000 1 0 2009 2012
Entrez Id: 29072
Gene Symbol: SETD2
SETD2 		Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 28 0.424 0.846 1.00 0.300 None 1.000 2 5 2014 2014
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 45 0.424 0.808 2.6E-12 0.330 None 1.000 1 0 2010 2017
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		Q01196 RUNX family transcription factor 1 Transcription factor 21 0.425 0.808 0.65 0.400 None 0.990 1 0 1995 2019
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP 		Q92793 CREB binding protein 31 0.428 0.808 1.00 0.350 None 1.000 0 0 2000 2018
Entrez Id: 613
Gene Symbol: BCR
BCR 		P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 17 0.431 0.885 0.99 0.500 None 0.978 0 0 1988 2020
Entrez Id: 25
Gene Symbol: ABL1
ABL1 		P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 37 0.432 0.923 1.00 0.600 None 0.991 2 0 1987 2020
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		P15559 NAD(P)H quinone dehydrogenase 1 52 0.434 0.885 1.2E-09 0.350 None 1.000 2 0 2002 2014
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2 		Q04721 notch receptor 2 60 0.441 0.808 1.00 0.310 None 1.000 0 0 2013 2013
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 65 0.444 0.885 1.00 0.320 None 1.000 1 0 1994 2013
Entrez Id: 10
Gene Symbol: NAT2
NAT2 		P11245 N-acetyltransferase 2 Enzyme 39 0.451 0.885 3.3E-06 0.300 None 1.000 1 0 2012 2012
Entrez Id: 2078
Gene Symbol: ERG
ERG 		P11308 ETS transcription factor ERG Transcription factor 11 0.453 0.808 0.96 0.400 None 0.909 1 0 1990 2017
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1 		Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 47 0.457 0.769 2.2E-05 0.310 None 1.000 1 0 2012 2013
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		P05181 cytochrome P450 family 2 subfamily E member 1 61 0.459 0.885 8.1E-09 0.310 None 1.000 1 0 2002 2007
Entrez Id: 2033
Gene Symbol: EP300
EP300 		Q09472 E1A binding protein p300 40 0.459 0.846 1.00 0.330 None 1.000 0 0 2004 2017
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		P36888 fms related receptor tyrosine kinase 3 Kinase 22 0.462 0.654 0.61 0.800 None 1.000 0 4 2004 2020
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 20 0.467 0.808 2.2E-16 0.630 None 1.000 2 0 2001 2011
Entrez Id: 1021
Gene Symbol: CDK6
CDK6 		Q00534 cyclin dependent kinase 6 Kinase 40 0.471 0.731 0.98 0.310 None 1.000 1 0 2009 2014