Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 Biomarker disease CTD_human
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 GeneticVariation disease UNIPROT
Entrez Id: 2322
Gene Symbol: FLT3
FLT3 		0.800 CausalMutation disease CGI
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 Biomarker disease CTD_human Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options. 26214592 2015
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 GeneticVariation disease UNIPROT A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. 24013638 2013
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 Biomarker disease CTD_human Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. 19684604 2009
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 CausalMutation disease CGI
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.700 GenomicAlterations disease CGI
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.700 CausalMutation disease CGI
Entrez Id: 4683
Gene Symbol: NBN
NBN 		0.630 Biomarker disease GENOMICS_ENGLAND Four children with acute lymphoblastic leukemia have been reported to be heterozygous for a germline and/or somatic missense mutation in NBS1, leading to the I171V substitution. 15338273 2004
Entrez Id: 4683
Gene Symbol: NBN
NBN 		0.630 Biomarker disease GENOMICS_ENGLAND Mutations in the Nijmegen Breakage Syndrome gene (NBS1) in childhood acute lymphoblastic leukemia (ALL). 11325820 2001
Entrez Id: 4683
Gene Symbol: NBN
NBN 		0.630 Biomarker disease CTD_human
Entrez Id: 25
Gene Symbol: ABL1
ABL1 		0.600 Biomarker disease CTD_human Antileukaemia effect of rapamycin alone or in combination with daunorubicin on Ph+ acute lymphoblastic leukaemia cell line. 21898527 2012
Entrez Id: 64109
Gene Symbol: CRLF2
CRLF2 		0.600 Biomarker disease CTD_human Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. 19838194 2009
Entrez Id: 25
Gene Symbol: ABL1
ABL1 		0.600 Biomarker disease CTD_human In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups. 11984797 2002
Entrez Id: 25
Gene Symbol: ABL1
ABL1 		0.600 CausalMutation disease CGI
Entrez Id: 64109
Gene Symbol: CRLF2
CRLF2 		0.600 CausalMutation disease CGI
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3 		0.530 Biomarker disease GENOMICS_ENGLAND Genetic loss of SH2B3 in acute lymphoblastic leukemia. 23908464 2013
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3 		0.530 CausalMutation disease CGI
Entrez Id: 613
Gene Symbol: BCR
BCR 		0.500 Biomarker disease CTD_human
Entrez Id: 84159
Gene Symbol: ARID5B
ARID5B 		0.480 Biomarker disease CTD_human Germline genomic variants associated with childhood acute lymphoblastic leukemia. 19684603 2009
Entrez Id: 84159
Gene Symbol: ARID5B
ARID5B 		0.480 Biomarker disease CTD_human Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. 19684604 2009
Entrez Id: 6886
Gene Symbol: TAL1
TAL1 		0.460 Biomarker disease CTD_human
Entrez Id: 8021
Gene Symbol: NUP214
NUP214 		0.420 Biomarker disease CTD_human
Entrez Id: 3981
Gene Symbol: LIG4
LIG4 		0.410 Biomarker disease GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017