Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.979 1 0 1990 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 1.000 None 0.959 6 67 1990 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 0.989 4 0 1988 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.400 None 0.986 1 0 1990 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.800 None 0.966 1 11 2002 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.985 1 0 1985 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 80 0.299 0.962 3.7E-03 0.400 None 0.958 1 0 1990 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.700 None 0.984 2 3 1996 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.800 strong 0.982 5 16 1998 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.964 1 0 1996 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.600 None 0.990 1 0 1999 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 109 0.310 0.962 2.7E-04 0.400 None 0.978 1 0 1990 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.600 None 0.957 5 0 1999 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 119 0.318 0.885 0.27 0.400 None 0.962 1 0 1989 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.380 None 1.000 1 0 2003 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.700 None 0.920 2 2 1985 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 80 0.321 0.962 4.6E-09 0.400 None 1.000 1 0 2011 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.400 None 0.980 2 0 1995 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 25 0.324 0.923 1.9E-02 0.400 None 0.968 1 0 2009 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 48 0.325 0.923 0.99 0.400 None 0.972 2 0 1997 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.400 None 1.000 1 0 2003 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 98 0.333 0.923 0.84 0.400 None 0.963 1 0 1996 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 68 0.343 0.885 1.00 0.400 None 0.983 1 0 2007 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 0.967 5 0 1993 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.600 None 1.000 4 0 1985 2020