Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 1.000 None 0.959 635 17 1990 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 1.000 None 0.969 60 1 1994 2020
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 389 0.404 0.923 3.7E-06 0.900 None 1.000 19 1 1998 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.800 strong 0.982 384 7 1998 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.800 None 0.966 174 5 2002 2020
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A 		P20823 HNF1 homeobox A Nucleic acid binding 205 0.478 0.846 0.96 0.800 None 0.931 29 0 1990 2019
Entrez Id: 8312
Gene Symbol: AXIN1
AXIN1 		O15169 axin 1 95 0.559 0.577 0.41 0.800 None 0.944 17 1 2000 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.700 None 0.984 118 0 1996 2019
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		P01344 insulin like growth factor 2 477 0.390 0.885 4.4E-02 0.700 None 0.987 70 0 1989 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 517 0.373 0.962 1.00 0.700 None 0.963 27 0 1993 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.700 None 0.920 23 2 1985 2020
Entrez Id: 3482
Gene Symbol: IGF2R
IGF2R 		P11717 insulin like growth factor 2 receptor Receptor 133 0.518 0.731 1.00 0.700 None 1.000 13 2 1995 2019
Entrez Id: 2719
Gene Symbol: GPC3
GPC3 		P51654 glypican 3 186 0.466 0.808 1.00 0.600 None 0.984 186 1 1997 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.600 None 0.990 100 2 1999 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 839 0.344 0.885 1.3E-05 0.600 None 0.960 97 6 1991 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.600 None 0.957 86 4 1999 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 525 0.374 0.846 0.99 0.600 None 0.977 77 4 1998 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.600 None 1.000 69 0 1985 2020
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1 		Q08050 forkhead box M1 307 0.441 0.769 7.4E-04 0.600 None 1.000 47 0 1992 2019
Entrez Id: 983
Gene Symbol: CDK1
CDK1 		P06493 cyclin dependent kinase 1 Kinase 207 0.482 0.808 0.99 0.600 None 1.000 29 0 1999 2019
Entrez Id: 6502
Gene Symbol: SKP2
SKP2 		Q13309 S-phase kinase associated protein 2 184 0.492 0.808 0.96 0.600 None 1.000 26 0 1998 2019
Entrez Id: 27232
Gene Symbol: GNMT
GNMT 		Q14749 glycine N-methyltransferase 41 0.626 0.462 2.8E-03 0.600 None 0.962 25 0 1998 2019
Entrez Id: 7039
Gene Symbol: TGFA
TGFA 		P01135 transforming growth factor alpha Signaling 332 0.432 0.885 0.72 0.600 None 1.000 21 0 1992 2016
Entrez Id: 5747
Gene Symbol: PTK2
PTK2 		Q05397 protein tyrosine kinase 2 Kinase 168 0.497 0.808 1.00 0.600 None 1.000 19 0 2003 2020
Entrez Id: 57817
Gene Symbol: HAMP
HAMP 		P81172 hepcidin antimicrobial peptide 327 0.433 0.846 8.2E-03 0.600 None 0.950 19 0 2005 2019