Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 15 1 2012 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.090 None 1.000 9 0 2014 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.090 None 1.000 9 1 2015 2019
Entrez Id: 10000
Gene Symbol: AKT3
AKT3 		Q9Y243 AKT serine/threonine kinase 3 Kinase 183 0.512 0.808 1.00 0.070 None 1.000 7 0 2013 2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.070 None 1.000 7 0 2014 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.070 None 1.000 7 1 2014 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.070 None 1.000 7 0 2014 2019
Entrez Id: 23209
Gene Symbol: MLC1
MLC1 		Q15049 modulator of VRAC current 1 Ion channel 87 0.585 0.769 3.2E-08 0.020 None 1.000 2 0 2013 2015
Entrez Id: 5296
Gene Symbol: PIK3R2
PIK3R2 		O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 120 0.551 0.808 1.6E-02 0.020 None 1.000 2 0 2015 2016
Entrez Id: 5058
Gene Symbol: PAK1
PAK1 		Q13153 p21 (RAC1) activated kinase 1 Kinase 221 0.494 0.808 1.3E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8738
Gene Symbol: CRADD
CRADD 		P78560 CASP2 and RIPK1 domain containing adaptor with death domain 76 0.619 0.500 0.88 0.010 None 1.000 1 0 2016 2016
Entrez Id: 8635
Gene Symbol: RNASET2
RNASET2 		O00584 ribonuclease T2 46 0.682 0.615 2.7E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 835
Gene Symbol: CASP2
CASP2 		P42575 caspase 2 Enzyme 105 0.565 0.731 1.5E-03 0.010 None 1.000 1 0 2016 2016
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 6009
Gene Symbol: RHEB
RHEB 		Q15382 Ras homolog, mTORC1 binding Enzyme modulator 53 0.631 0.577 0.98 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 604 0.398 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 22983
Gene Symbol: MAST1
MAST1 		Q9Y2H9 microtubule associated serine/threonine kinase 1 Kinase 41 0.711 0.385 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2688
Gene Symbol: GH1
GH1 		P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3161
Gene Symbol: HMMR
HMMR 		O75330 hyaluronan mediated motility receptor 117 0.544 0.615 5.5E-21 0.010 None 1.000 1 0 2017 2017
Entrez Id: 51256
Gene Symbol: TBC1D7
TBC1D7 		Q9P0N9 TBC1 domain family member 7 26 0.729 0.385 2.9E-12 0.010 None 1.000 1 0 2013 2013
Entrez Id: 8925
Gene Symbol: HERC1
HERC1 		Q15751 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 Enzyme modulator 57 0.674 0.500 1.00 0.010 None 1.000 1 0 2016 2016