Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.790 definitive 1.000 23 56 2008 2019
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.100 None 0 1
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 0 2
Entrez Id: 4361
Gene Symbol: MRE11
MRE11
P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.100 None 0 1
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 0 2
Entrez Id: 23405
Gene Symbol: DICER1
DICER1
Q9UPY3 dicer 1, ribonuclease III Enzyme 302 0.446 0.846 1.00 0.030 None 1.000 3 0 2012 2017
Entrez Id: 2271
Gene Symbol: FH
FH
P07954 fumarate hydratase Enzyme 231 0.489 0.846 8.8E-02 0.030 None 1.000 3 0 2005 2010
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7428
Gene Symbol: VHL
VHL
P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.010 None 1.000 1 0 2015 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 57670
Gene Symbol: KIAA1549
KIAA1549
Q9HCM3 KIAA1549 64 0.615 0.346 0.99 0.010 None 1.000 1 0 2014 2014
Entrez Id: 4771
Gene Symbol: NF2
NF2
P35240 neurofibromin 2 312 0.468 0.885 1.00 0.010 None 1.000 1 0 2002 2002
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 0.010 None 1.000 1 0 2017 2017
Entrez Id: 25913
Gene Symbol: POT1
POT1
Q9NUX5 protection of telomeres 1 Nucleic acid binding 107 0.560 0.731 0.85 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2119
Gene Symbol: ETV5
ETV5
P41161 ETS variant transcription factor 5 Transcription factor 121 0.565 0.731 1.00 0.010 None 1.000 1 0 2002 2002