Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 0.818 11 0 2002 2017
Entrez Id: 65065
Gene Symbol: NBEAL1
NBEAL1
Q6ZS30 neurobeachin like 1 60 0.638 0.692 5.1E-33 0.080 None 0.875 8 0 2017 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.080 None 1.000 8 0 2003 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.080 None 0.875 8 0 1997 2012
Entrez Id: 8600
Gene Symbol: TNFSF11
TNFSF11
O14788 TNF superfamily member 11 Signaling 327 0.453 0.846 4.9E-03 0.070 None 1.000 7 0 2000 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.070 None 0.857 7 0 2010 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.040 None 1.000 4 0 2004 2013
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
O00300 TNF receptor superfamily member 11b 443 0.422 0.808 0.16 0.030 None 1.000 3 0 2001 2008
Entrez Id: 5657
Gene Symbol: PRTN3
PRTN3
P24158 proteinase 3 Enzyme 215 0.503 0.808 3.8E-05 0.030 None 0.667 3 0 2010 2019
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
Q8IUH3 RNA binding motif protein 45 557 0.383 0.846 2.1E-10 0.030 None 1.000 3 0 1997 2007
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.030 None 1.000 3 0 2010 2011
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.030 None 1.000 3 0 2018 2020
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.030 None 1.000 3 0 2013 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.030 None 1.000 3 0 2010 2011
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.030 None 1.000 3 0 2000 2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 0 2009 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.030 None 1.000 3 0 2018 2019
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.030 None 1.000 3 0 2008 2019
Entrez Id: 7014
Gene Symbol: TERF2
TERF2
Q15554 telomeric repeat binding factor 2 125 0.541 0.731 0.99 0.020 None 1.000 2 0 2003 2008
Entrez Id: 406938
Gene Symbol: MIR146A
MIR146A
microRNA 146a 505 0.398 0.885 0.020 None 0.500 2 0 2017 2018
Entrez Id: 1513
Gene Symbol: CTSK
CTSK
P43235 cathepsin K Enzyme 221 0.497 0.808 3.1E-05 0.020 None 1.000 2 0 2002 2008
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
Q9UM07 peptidyl arginine deiminase 4 196 0.494 0.808 4.6E-16 0.020 None 1.000 2 0 2012 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.020 None 1.000 2 0 2017 2018
Entrez Id: 25842
Gene Symbol: ASF1A
ASF1A
Q9Y294 anti-silencing function 1A histone chaperone Nucleic acid binding 36 0.670 0.615 0.81 0.020 None 1.000 2 0 2017 2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 400 0.438 0.846 3.5E-21 0.020 None 1.000 2 0 2011 2016