Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 20 2 2004 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 14 0 2008 2018
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.100 None 1.000 10 1 2012 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 1.000 10 0 2008 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.060 None 1.000 6 0 2003 2019
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.050 None 1.000 5 1 2000 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.040 None 1.000 4 0 2010 2014
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12 		P59046 NLR family pyrin domain containing 12 95 0.569 0.846 3.6E-28 0.030 None 1.000 3 0 2011 2019
Entrez Id: 4598
Gene Symbol: MVK
MVK 		Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.030 None 1.000 3 0 2003 2019
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1 		O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 54 0.650 0.577 2.5E-06 0.020 None 0.500 2 1 2019 2019
Entrez Id: 58484
Gene Symbol: NLRC4
NLRC4 		Q9NPP4 NLR family CARD domain containing 4 145 0.556 0.769 9.9E-12 0.020 None 1.000 2 0 2014 2017
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		P01889 major histocompatibility complex, class I, B 706 0.379 0.885 3.9E-05 0.020 None 1.000 2 0 2019 2019
Entrez Id: 51816
Gene Symbol: ADA2
ADA2 		Q9NZK5 adenosine deaminase 2 Enzyme 165 0.545 0.846 8.1E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 92579
Gene Symbol: G6PC3
G6PC3 		Q9BUM1 glucose-6-phosphatase catalytic subunit 3 79 0.606 0.731 4.7E-06 0.010 None 1.000 1 0 2017 2017
Entrez Id: 26525
Gene Symbol: IL36RN
IL36RN 		Q9UBH0 interleukin 36 receptor antagonist 47 0.638 0.538 3.4E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2737
Gene Symbol: GLI3
GLI3 		P10071 GLI family zinc finger 3 400 0.436 0.846 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 90268
Gene Symbol: OTULIN
OTULIN 		Q96BN8 OTU deubiquitinase with linear linkage specificity 26 0.751 0.346 0.22 0.010 None 1.000 1 0 2018 2018
Entrez Id: 8737
Gene Symbol: RIPK1
RIPK1 		Q13546 receptor interacting serine/threonine kinase 1 Kinase 250 0.479 0.769 7.9E-03 0.010 None 1.000 1 0 2020 2020
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.010 None 1.000 1 0 2012 2012
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3 		P21580 TNF alpha induced protein 3 Enzyme 212 0.481 0.808 1.00 0.010 None 1.000 1 1 2019 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1519 0.288 0.962 0.47 0.010 None 1.000 1 0 2015 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5069
Gene Symbol: PAPPA
PAPPA 		Q13219 pappalysin 1 125 0.558 0.692 0.16 0.010 None 1.000 1 0 2017 2017
Entrez Id: 9948
Gene Symbol: WDR1
WDR1 		O75083 WD repeat domain 1 Cellular structure 59 0.623 0.654 1.00 0.010 None 1.000 1 0 2018 2018