Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3075
Gene Symbol: CFH
CFH
P08603 complement factor H 393 0.441 0.885 0.86 0.400 strong 1.000 15 1 2012 2018
Entrez Id: 81494
Gene Symbol: CFHR5
CFHR5
Q9BXR6 complement factor H related 5 43 0.659 0.385 2.1E-32 0.370 None 1.000 9 0 2011 2018
Entrez Id: 718
Gene Symbol: C3
C3
P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.330 strong 1.000 4 0 2014 2019
Entrez Id: 3078
Gene Symbol: CFHR1
CFHR1
Q03591 complement factor H related 1 90 0.588 0.615 2.6E-08 0.320 strong 1.000 4 0 2007 2017
Entrez Id: 4179
Gene Symbol: CD46
CD46
P15529 CD46 molecule 258 0.477 0.808 4.7E-07 0.310 limited 1.000 2 0 2011 2016
Entrez Id: 3080
Gene Symbol: CFHR2
CFHR2
P36980 complement factor H related 2 12 0.769 0.346 1.5E-08 0.300 strong 1.000 2 0 2014 2016
Entrez Id: 629
Gene Symbol: CFB
CFB
P00751 complement factor B 139 0.532 0.769 4.7E-16 0.300 strong 1.000 1 0 2016 2016
Entrez Id: 3426
Gene Symbol: CFI
CFI
P05156 complement factor I 133 0.569 0.731 3.5E-08 0.300 strong 1.000 1 0 2016 2016
Entrez Id: 8526
Gene Symbol: DGKE
DGKE
P52429 diacylglycerol kinase epsilon Enzyme 41 0.674 0.538 5.5E-06 0.300 strong 1.000 1 0 2017 2017
Entrez Id: 5199
Gene Symbol: CFP
CFP
P27918 complement factor properdin 108 0.573 0.692 0.69 0.020 None 1.000 2 0 2017 2018
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
P21730 complement C5a receptor 1 G-protein coupled receptor 179 0.513 0.808 0.40 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7056
Gene Symbol: THBD
THBD
P07204 thrombomodulin 303 0.457 0.769 5.4E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 10878
Gene Symbol: CFHR3
CFHR3
Q02985 complement factor H related 3 55 0.663 0.462 1.7E-11 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3852
Gene Symbol: KRT5
KRT5
P13647 keratin 5 203 0.512 0.731 0.64 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1378
Gene Symbol: CR1
CR1
P17927 complement C3b/C4b receptor 1 (Knops blood group) 129 0.533 0.808 1.6E-35 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12
P59046 NLR family pyrin domain containing 12 95 0.569 0.846 3.6E-28 0.010 None 1.000 1 0 2018 2018