Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.938 32 0 2011 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.080 None 1.000 8 0 2017 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.050 None 1.000 5 0 2015 2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.050 None 1.000 5 0 2012 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.030 None 1.000 3 0 2013 2019
Entrez Id: 54567
Gene Symbol: DLL4
DLL4
Q9NR61 delta like canonical Notch ligand 4 219 0.494 0.769 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 10630
Gene Symbol: PDPN
PDPN
Q86YL7 podoplanin 256 0.470 0.769 3.2E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.010 None 1.000 1 0 2018 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2014 2014
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
P43699 NK2 homeobox 1 Transcription factor 319 0.457 0.808 0.36 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7270
Gene Symbol: TTF1
TTF1
Q15361 transcription termination factor 1 134 0.537 0.500 6.2E-13 0.010 None 1.000 1 0 2015 2015
Entrez Id: 799
Gene Symbol: CALCR
CALCR
P30988 calcitonin receptor G-protein coupled receptor 282 0.464 0.846 3.1E-09 0.010 None 1.000 1 0 2018 2018
Entrez Id: 84335
Gene Symbol: AKT1S1
AKT1S1
Q96B36 AKT1 substrate 1 55 0.615 0.385 0.11 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8784
Gene Symbol: TNFRSF18
TNFRSF18
Q9Y5U5 TNF receptor superfamily member 18 53 0.631 0.538 1.5E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5287
Gene Symbol: PIK3C2B
PIK3C2B
O00750 phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta Kinase 33 0.691 0.462 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 201633
Gene Symbol: TIGIT
TIGIT
Q495A1 T cell immunoreceptor with Ig and ITIM domains 56 0.623 0.538 1.8E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 23373
Gene Symbol: CRTC1
CRTC1
Q6UUV9 CREB regulated transcription coactivator 1 Transcription factor 115 0.565 0.692 0.53 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
P04792 heat shock protein family B (small) member 1 395 0.436 0.808 2.8E-07 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3316
Gene Symbol: HSPB2
HSPB2
Q16082 heat shock protein family B (small) member 2 290 0.457 0.769 3.3E-04 0.010 None 1.000 1 0 2017 2017