Source: CLINVAR ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 153 0.385 0.923 1.00 0.910 None 1.000 50 40 2001 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 45 0.418 0.885 0.85 0.400 None 1.000 0 1 2007 2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.400 None 1.000 0 1 2007 2007
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 37 0.390 0.808 0.49 0.400 None 1.000 0 4 2010 2010
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 26 0.439 0.846 0.90 0.400 None 1.000 0 2 2007 2007
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 125 0.319 0.846 1.00 0.400 None 1.000 0 8 2007 2007
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 62 0.485 0.808 1.00 0.400 None 1.000 0 8 2007 2007
Entrez Id: 6655
Gene Symbol: SOS2
SOS2 		Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 2 0.608 0.692 1.00 0.100 None 1.000 1 1 2015 2015
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		Q92963 Ras like without CAAX 1 Enzyme modulator 44 0.527 0.808 0.13 0.100 None 0 6
Entrez Id: 22800
Gene Symbol: RRAS2
RRAS2 		P62070 RAS related 2 Enzyme modulator 2 0.656 0.500 0.97 0.100 None 0 1
Entrez Id: 867
Gene Symbol: CBL
CBL 		P22681 Cbl proto-oncogene Enzyme 19 0.527 0.769 6.1E-04 0.100 None 0 1