Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 0.976 124 0 2000 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.050 None 1.000 5 0 2008 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.040 None 1.000 4 0 2010 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.040 None 1.000 4 0 2004 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.030 None 1.000 3 0 2009 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.030 None 1.000 3 0 2010 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.030 None 1.000 3 0 2010 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.030 None 1.000 3 0 2010 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.020 None 1.000 2 0 2012 2017
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
P07900 heat shock protein 90 alpha family class A member 1 Chaperone 455 0.411 0.923 0.86 0.020 None 1.000 2 0 2011 2017
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.020 None 1.000 2 0 2012 2013
Entrez Id: 51155
Gene Symbol: JPT1
JPT1
Q9UK76 Jupiter microtubule associated homolog 1 32 0.695 0.538 2.5E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase non-receptor type 2 134 0.538 0.692 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 2012 2012
Entrez Id: 9622
Gene Symbol: KLK4
KLK4
Q9Y5K2 kallikrein related peptidase 4 Enzyme 110 0.559 0.692 4.5E-06 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9148
Gene Symbol: NEURL1
NEURL1
O76050 neuralized E3 ubiquitin protein ligase 1 Enzyme 103 0.556 0.538 1.1E-02 0.010 None 1.000 1 0 2009 2009
Entrez Id: 7538
Gene Symbol: ZFP36
ZFP36
P26651 ZFP36 ring finger protein Nucleic acid binding 161 0.523 0.692 0.75 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7203
Gene Symbol: CCT3
CCT3
P49368 chaperonin containing TCP1 subunit 3 Chaperone 43 0.650 0.577 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
P11388 DNA topoisomerase II alpha 200 0.497 0.731 0.99 0.010 None 1.000 1 0 2012 2012
Entrez Id: 7138
Gene Symbol: TNNT1
TNNT1
P13805 troponin T1, slow skeletal type Cellular structure 60 0.633 0.577 7.0E-14 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4758
Gene Symbol: NEU1
NEU1
Q99519 neuraminidase 1 Enzyme 207 0.513 0.769 7.3E-05 0.010 None 1.000 1 0 2009 2009
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.010 None 1.000 1 0 2014 2014