Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 26166
Gene Symbol: RGS22
RGS22 		Q8NE09 regulator of G protein signaling 22 20 0.780 0.154 1.6E-30 0.110 None 1.000 1 1 2014 2014
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.110 None 1.000 1 1 2017 2017
Entrez Id: 2191
Gene Symbol: FAP
FAP 		Q12884 fibroblast activation protein alpha Enzyme 216 0.496 0.808 1.9E-28 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 244 0.484 0.808 4.5E-27 0.110 None 1.000 1 0 2008 2008
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		P10635 cytochrome P450 family 2 subfamily D member 6 432 0.437 0.885 1.1E-25 0.070 None 1.000 7 0 1996 2006
Entrez Id: 22909
Gene Symbol: FAN1
FAN1 		Q9Y2M0 FANCD2 and FANCI associated nuclease 1 93 0.610 0.577 1.7E-25 0.100 None 0 0
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.110 None 1.000 1 1 2010 2010
Entrez Id: 4317
Gene Symbol: MMP8
MMP8 		P22894 matrix metallopeptidase 8 Enzyme 213 0.488 0.808 1.1E-24 0.010 None 1.000 1 0 2008 2008
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.100 None 0 1
Entrez Id: 2041
Gene Symbol: EPHA1
EPHA1 		P21709 EPH receptor A1 Kinase 119 0.544 0.731 1.5E-23 0.010 None 1.000 1 0 2006 2006
Entrez Id: 3034
Gene Symbol: HAL
HAL 		P42357 histidine ammonia-lyase 57 0.641 0.538 2.5E-23 0.010 None 1.000 1 1 2008 2008
Entrez Id: 1591
Gene Symbol: CYP24A1
CYP24A1 		Q07973 cytochrome P450 family 24 subfamily A member 1 Enzyme 171 0.518 0.692 3.2E-23 0.020 None 1.000 2 0 2004 2017
Entrez Id: 1429
Gene Symbol: CRYZ
CRYZ 		Q08257 crystallin zeta 145 0.524 0.731 5.7E-23 0.010 None 1.000 1 0 1999 1999
Entrez Id: 130540
Gene Symbol: FLACC1
FLACC1 		Q96Q35 flagellum associated containing coiled-coil domains 1 18 0.729 0.269 1.3E-22 0.010 None 1.000 1 2 2015 2015
Entrez Id: 824
Gene Symbol: CAPN2
CAPN2 		P17655 calpain 2 Enzyme 87 0.590 0.692 3.5E-22 0.010 None 1.000 1 0 2003 2003
Entrez Id: 353174
Gene Symbol: ZACN
ZACN 		Q401N2 zinc activated ion channel 42 0.659 0.538 4.3E-22 0.010 None 1.000 1 0 2005 2005
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6 		P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 257 0.507 0.808 5.2E-22 0.010 None 1.000 1 2 2012 2012
Entrez Id: 1830
Gene Symbol: DSG3
DSG3 		P32926 desmoglein 3 Cell adhesion 78 0.603 0.654 1.5E-20 0.010 None 1.000 1 0 2014 2014
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.170 None 0.857 7 2 1999 2014
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 0 1
Entrez Id: 1593
Gene Symbol: CYP27A1
CYP27A1 		Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 167 0.538 0.731 5.3E-19 0.010 None 1.000 1 0 2016 2016
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6 		Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 400 0.431 0.885 8.6E-19 0.010 None 1.000 1 0 1997 1997
Entrez Id: 10384
Gene Symbol: BTN3A3
BTN3A3 		O00478 butyrophilin subfamily 3 member A3 Enzyme modulator 12 0.792 0.308 1.2E-18 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4311
Gene Symbol: MME
MME 		P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.020 None 1.000 2 0 2018 2018
Entrez Id: 28965
Gene Symbol: SLC27A6
SLC27A6 		Q9Y2P4 solute carrier family 27 member 6 Transporter 26 0.722 0.346 2.4E-18 0.010 None 1.000 1 0 2019 2019