Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.060 Biomarker phenotype BEFREE In univariate analysis, ileo-colonic location (odds ratio [OR] 1.88, p = 0.0148), perianal CD [OR 7.01, p = 0.0004], fever [OR 1.88, p = 0.0247], neutrophil-to-lymphocyte ratio [OR 1.12, p < 0.0001], and C-reactive protein [OR 1.10, p < 0.0001] were significantly associated with abscess formation, whereas current use of corticosteroids was negatively associated with abscess formation [OR 0.46, 95% CI, 0.2-0.88, p = 0.0192]. 30768181 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.060 AlteredExpression phenotype BEFREE Parameters including the operation time, blood loss, time of ESR and CRP decreasing to the normal level, time of abscess disappearance, time of bone graft fusion, rate of surgical complications, Visual Analog Scale (VAS) score, kyphosis angle and SF-36 scale were compared between two groups to evaluate their therapeutic effects. 31775707 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.060 AlteredExpression phenotype BEFREE White blood cell counts and C-reactive protein levels were not significantly different between patients with an abscess and those without. 29888695 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.060 AlteredExpression phenotype BEFREE We also analysed other risk factors for postoperative complications, such as patient age, previous surgeries, preoperative C-reactive protein, faecal calprotectin, albumin and haemoglobin levels, American Society of Anesthesiologists (ASA) classification, preoperative immunosuppressive medication, surgical approach and the presence of intraoperative fistula or abscess. 29431516 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.060 AlteredExpression phenotype BEFREE In a cohort with right-sided abdominal pain, perforation should be considered in children with high CRP levels and free fluids or abscess formation on ultrasound. 27872360 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.060 AlteredExpression phenotype BEFREE Multivariate analysis showed that presence of immature polymorphonuclear leukocytes in peripheral blood (odds ratio [OR], 3.67; 95% confidence interval [CI], 1.08-12.63), high C-reactive protein levels (>12 mg/dL) (OR, 5.24; 95% CI, 1.10-24.93), and no underlying disease at presentation (OR, 5.48; 95% CI, 1.06-28.25) were independent predictors of the occurrence of necrosis or/and abscess. 14999627 2004
Entrez Id: 847
Gene Symbol: CAT
CAT
0.050 Biomarker phenotype BEFREE Gram-stain-positive, partially acid-fast, non-spore-forming, anaerobic, catalase-positive, pleomorphic bacteria were isolated from human abscesses. 27130323 2016
Entrez Id: 847
Gene Symbol: CAT
CAT
0.050 Biomarker phenotype BEFREE Helcococcus spp. are Gram-positive, catalase-negative, facultatively anaerobic cocci that are associated with wound and prosthetic joint infections as well bacteremia and empyema.Five Helcococcus spp. strains were isolated from our patient population, including 2 strains of Helcococcus kunzii from trauma-associated wounds, 2 Helcococcus sueciensis strains from blood and abscess, and a novel Helcococcus spp. strain from blood associated with urosepsis. 24371247 2014
Entrez Id: 847
Gene Symbol: CAT
CAT
0.050 GeneticVariation phenotype BEFREE Molecular characterization of a catalase-negative methicillin-susceptible Staphylococcus aureus subsp. aureus strain collected from a patient with cutaneous abscess. 24131694 2014
Entrez Id: 847
Gene Symbol: CAT
CAT
0.050 Biomarker phenotype BEFREE The PerR-regulated katA gene encodes the sole catalase of S. aureus, which is an important starvation survival determinant but is surprisingly not required for pathogenicity in a murine skin abscess model of infection. 11349039 2001
Entrez Id: 847
Gene Symbol: CAT
CAT
0.050 Biomarker phenotype BEFREE Five male patients from four different families presented with a clinical record of chronic granulomatous disease (CGD): recurrent infections of the skin and/or respiratory tract with catalase-positive microorganisms, sometimes in combination with granulomata and/or abscesses in various organs. 1431553 1992
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6
0.040 Biomarker phenotype BEFREE Our patient received adequate drainage of MRSA abscesses and a complete course of antibiotics. 29390368 2017
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6
0.040 Biomarker phenotype BEFREE SpA(KKAA) MAbs promoted opsonophagocytic killing of MRSA in mouse and human blood, provided protection from abscess formation, and stimulated pathogen-specific immune responses in a mouse model of staphylococcal disease. 22825452 2012
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6
0.040 Biomarker phenotype BEFREE All MRSA isolates from colonization and abscesses were the same, albeit with a variant in pulsed-field gel electrophoresis analysis. 22160592 2012
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6
0.040 Biomarker phenotype BEFREE We identified only 1 Panton-Valentine leukocidin (PVL)-positive MRSA strain, which belonged to SCCmec type V. The PVL-positive CA-MRSA strain was isolated from a patient with multiple subcutaneous abscesses. 22446128 2012
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.030 Biomarker phenotype BEFREE Rather, LM49 treatment inhibited inflammatory cell infiltration or abscess and improved tissue lesions in the renal medullary junction, renal pelvis, and calyx, and high-dose LM49 treatment inhibited the production of inflammatory interleukin-1β (IL-1β) and interleukin-6 (IL-6) in serum. 30007245 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.030 Biomarker phenotype BEFREE In a mouse abscess model, the type II clones significantly induced serum IL-1beta and IL-6, as well as other infectious symptoms. 17081195 2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.030 GeneticVariation phenotype BEFREE A significant association was observed between the occurrence of the GG genotype or the G allele expression of the polymorphic locus-174 (G/C) of the IL6 gene, and the presence of the symptomatic dental abscesses in women and in individuals < or =35 years old. 17511783 2007
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.020 GeneticVariation phenotype BEFREE Few data are available on the effects of tumor necrosis factor (TNF) antagonist therapy for patients with internal fistulizing Crohn's disease (CD) and there is debate over the risk of abscess. 31128337 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
0.020 AlteredExpression phenotype BEFREE Univariate analysis showed that male gender, diabetes, pleuritic symptoms, white blood cells >10×109/L, albumin level <25 g/L, and positive sputum cultures were potential clinical-related risk factors and that an abscess >5 cm in diameter and transpulmonary fissure abscesses were potential computed tomography imaging-related risk factors for pulmonary abscess-related empyema. 30994710 2019
Entrez Id: 79447
Gene Symbol: PAGR1
PAGR1
0.020 Biomarker phenotype BEFREE The homeless are disproportionately affected by GAS and have a higher rate of abscesses and high mortality. 30684741 2019
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
0.020 GeneticVariation phenotype BEFREE Four children underwent surgery in the ENT diagnostic group: two retro-pharyngeal abscesses, one paracentesis and one cervicectomy. 30903929 2019
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
0.020 Biomarker phenotype BEFREE CD44 and CD73 immunostaining was observed in mesenchymal cells located in the outer portion of the abscess and periapical cyst specimens. 31060815 2019
Entrez Id: 2588
Gene Symbol: GALNS
GALNS
0.020 Biomarker phenotype BEFREE The homeless are disproportionately affected by GAS and have a higher rate of abscesses and high mortality. 30684741 2019
Entrez Id: 2520
Gene Symbol: GAST
GAST
0.020 Biomarker phenotype BEFREE The homeless are disproportionately affected by GAS and have a higher rate of abscesses and high mortality. 30684741 2019