Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 115908
Gene Symbol: CTHRC1
CTHRC1 		0.410 Biomarker disease CTD_human
Entrez Id: 4481
Gene Symbol: MSR1
MSR1 		0.410 Biomarker disease CTD_human
Entrez Id: 115908
Gene Symbol: CTHRC1
CTHRC1 		0.410 Biomarker disease HPO
Entrez Id: 4481
Gene Symbol: MSR1
MSR1 		0.410 Biomarker disease HPO
Entrez Id: 51008
Gene Symbol: ASCC1
ASCC1 		0.410 Biomarker disease HPO
Entrez Id: 51008
Gene Symbol: ASCC1
ASCC1 		0.410 Biomarker disease CTD_human
Entrez Id: 2271
Gene Symbol: FH
FH 		0.100 Biomarker disease HPO
Entrez Id: 5885
Gene Symbol: RAD21
RAD21 		0.100 Biomarker disease HPO
Entrez Id: 1540
Gene Symbol: CYLD
CYLD 		0.040 Biomarker disease BEFREE <b>Methods</b> Patients referred with histologically proven HGD or EAC to two Dutch BE expert centers were included. 27855466 2017
Entrez Id: 574455
Gene Symbol: MIR193B
MIR193B 		0.010 AlteredExpression disease BEFREE 5‑Azacytidine treatment resulted in a significant upregulation of miR‑193b in BE and esophageal cancer cells. 27176876 2016
Entrez Id: 64778
Gene Symbol: FNDC3B
FNDC3B 		0.010 Biomarker disease BEFREE 6 target DEGs demonstrated higher-degree distributions in the network, and ROC analysis indicated that FNDC3B may be the best potential biomarker for BE diagnosis. 29417867 2018
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC 		0.060 AlteredExpression disease BEFREE Barrett's oesophagus strongly expressed MUC5AC and MUC3 in the superficial columnar epithelium, MUC2 in the goblet cells, and MUC6 in the glands. 11076872 2000
Entrez Id: 4584
Gene Symbol: MUC3A
MUC3A 		0.020 AlteredExpression disease BEFREE Barrett's oesophagus strongly expressed MUC5AC and MUC3 in the superficial columnar epithelium, MUC2 in the goblet cells, and MUC6 in the glands. 11076872 2000
Entrez Id: 140453
Gene Symbol: MUC17
MUC17 		0.010 AlteredExpression disease BEFREE Barrett's oesophagus strongly expressed MUC5AC and MUC3 in the superficial columnar epithelium, MUC2 in the goblet cells, and MUC6 in the glands. 11076872 2000
Entrez Id: 57876
Gene Symbol: MUC3B
MUC3B 		0.010 AlteredExpression disease BEFREE Barrett's oesophagus strongly expressed MUC5AC and MUC3 in the superficial columnar epithelium, MUC2 in the goblet cells, and MUC6 in the glands. 11076872 2000
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.100 Biomarker disease BEFREE Barrett's esophagus is thought to progress to esophageal adenocarcinoma (EAC) through a stepwise progression with loss of CDKN2A followed by TP53 inactivation and aneuploidy. 26192918 2015
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.010 Biomarker disease BEFREE Barrett's esophagus epithelium cells (BAR-T) were incubated with acid and bile salts in the presence or absence of the TLR2 agonist Pam3CSK4 for a period up to 4 weeks. 27689189 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.100 AlteredExpression disease BEFREE HER-2/neu protein overexpression has been associated with poor prognosis in a variety of tumors, but its significance in Barrett's esophagus-associated adenocarcinoma (BEAd) is unknown. 10665910 2000
Entrez Id: 7015
Gene Symbol: TERT
TERT 		0.030 AlteredExpression disease BEFREE Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence. 10675236 2000
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.070 Biomarker disease BEFREE Cyclin D1-positive staining could be a useful biomarker in identifying Barrett's esophagus patients at high risk of esophageal adenocarcinoma. 10944553 2000
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.100 AlteredExpression disease BEFREE Her-2/neu gene amplification, elevated mRNA expression, and protein overexpression in the metaplasia-dysplasia-adenocarcinoma sequence of Barrett's esophagus. 11406641 2001
Entrez Id: 4316
Gene Symbol: MMP7
MMP7 		0.010 AlteredExpression disease BEFREE Matrilysin and metalloelastase were upregulated already in BE. 11487270 2001
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.070 Biomarker disease BEFREE Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action. 12203119 2002
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.060 AlteredExpression disease BEFREE C-myc protein was upregulated in 50% of Barrett's metaplasia and 90% of oesophageal adenocarcinoma samples compared with squamous, gastric, and duodenal controls. 12524396 2003
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.030 AlteredExpression disease BEFREE Vascular endothelial growth factor and basic fibroblast growth factor expression in esophageal adenocarcinoma and Barrett esophagus. 12579092 2003