Gene: CLOCK ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease BEFREE A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder. 18789374 2008
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease BEFREE We had previously identified the clock gene D-box binding protein (Dbp) as a potential candidate gene for bipolar disorder and for alcoholism, using a Convergent Functional Genomics (CFG) approach. 18247375 2008
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease BEFREE A multi-locus interaction between rs6442925 in the 5' upstream of BHLHB2, rs1534891 in CSNK1E, and rs534654 near the 3' end of the CLOCK gene, however, is significantly associated with BP (P = 0.00000172). 18228528 2008
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease BEFREE We have assessed evidence for linkage and association involving polymorphisms in 10 circadian clock genes (ARNTL, CLOCK, CRY2, CSNK1epsilon, DBP, GSK3beta, NPAS2, PER1, PER2, and PER3) to BPAD. 16528748 2006
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease BEFREE One of the human circadian clock genes, cryptochrome 1 (Cry1) (located on 12q23-q24.1) was analyzed because of its close correspondence to a linkage hotspot for bipolar disorder. 15722957 2005
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease LHGDN This preliminary observation leads to hypothesize a role for the CLOCK gene polymorphism in the regulation of long-term illness recurrence in bipolar disorder. 14582141 2003
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 GeneticVariation disease BEFREE This preliminary observation leads to hypothesize a possible involvement of the CLOCK gene polymorphism in the sleep disregulations in MDD and BP. 12898572 2003
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease BEFREE The human Clock gene has been proposed as a possible candidate for disorders affected by alterations of circadian rhythm, including bipolar disorder and schizophrenia. 11511917 2001
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease BEFREE Clock genes, feedback loops and their possible role in the etiology of bipolar disorders: an integrative model. 10904433 2000
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.600 Biomarker disease MGD