Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9640
Gene Symbol: ZNF592
ZNF592
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 54877
Gene Symbol: ZCCHC2
ZCCHC2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 7466
Gene Symbol: WFS1
WFS1
0.310 AlteredExpression disease BEFREE We also quantified the expression levels of WFS1 mRNA in the postmortem brains of patients with bipolar disorder, depression, schizophrenia, and controls. 12565131 2003
Entrez Id: 7425
Gene Symbol: VGF
VGF
0.010 AlteredExpression disease BEFREE Therefore, we aimed to investigate the relationship between serum VGF levels in BD and MDD patients. 30575991 2019
Entrez Id: 7252
Gene Symbol: TSHB
TSHB
0.300 Biomarker disease CTD_human Thyrotrophin response to thyrotrophin-releasing hormone in unipolar and bipolar affective illness. 6455462 1981
Entrez Id: 7226
Gene Symbol: TRPM2
TRPM2
0.300 Biomarker disease CTD_human Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. 23602965 2013
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3
0.300 Biomarker disease CTD_human Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. 23602965 2013
Entrez Id: 9881
Gene Symbol: TRANK1
TRANK1
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
0.300 Biomarker disease PSYGENET The three genes, namely, tryptophan hydroxylase 2 (TPH2), kynurenine 3 monooxygenase (KMO) and kynurenine amino transferase 3 (KAT III) SNPs and haplotype association analysis was performed in 338 (266 major depression and 72 bipolar depression) unrelated Caucasian patients with major depressive episodes and 310 age, gender and ethnicity matched controls. 21492941 2011
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
0.010 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 Biomarker disease BEFREE Moreover, logistic regression analyses correctly classified BD and MDD patients with 98.1% accuracy, using a combination of IL-6, IL-8, ST2, sTNFR2 (directly associated with BD) and IL-12 and TNF-α (directly associated with MDD). 31693974 2020
Entrez Id: 221981
Gene Symbol: THSD7A
THSD7A
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 26011
Gene Symbol: TENM4
TENM4
0.300 Biomarker disease CTD_human Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. 21926972 2011
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.010 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
0.300 Biomarker disease CTD_human NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD. 19204064 2010
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
0.300 Biomarker disease CTD_human Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia. 15845098 2005
Entrez Id: 6789
Gene Symbol: STK4
STK4
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 57519
Gene Symbol: STARD9
STARD9
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 23635
Gene Symbol: SSBP2
SSBP2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 6733
Gene Symbol: SRPK2
SRPK2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 6671
Gene Symbol: SP4
SP4
0.300 Biomarker disease CTD_human Transcription factor SP4 is a susceptibility gene for bipolar disorder. 19401786 2009
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.520 Biomarker disease PSYGENET The serotonin transporter (5-HTT) is the selective site of action of most proserotonergic compounds used to treat bipolar depression. 11386982 2001
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.520 Biomarker disease BEFREE The aim of the present study was to investigate for the presence of linkage disequilibrium between SLC6A4 and BP disorder. 10898918 2000
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.520 Biomarker disease PSYGENET The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). 10898918 2000