Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26277
Gene Symbol: TINF2
TINF2
0.300 Biomarker group CTD_human TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita. 18252230 2008
Entrez Id: 94160
Gene Symbol: ABCC12
ABCC12
0.300 Biomarker group CTD_human Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents. 18466103 2008
Entrez Id: 4835
Gene Symbol: NQO2
NQO2
0.300 Biomarker group CTD_human Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. 12351651 2002
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.050 Biomarker group BEFREE The Human T-cell Lymphotropic Virus (HTLV-1) is a Deltaretrovírus that was first isolated in the 1970s, and associated with Adult T-cell Leucemia-Lymphoma (ATLL), and subsequently to Tropical Spastic Paraparesis-Myelopathy (TSP/HAM). 29558516 2018
Entrez Id: 55729
Gene Symbol: ATF7IP
ATF7IP
0.050 Biomarker group BEFREE The Human T-cell Lymphotropic Virus (HTLV-1) is a Deltaretrovírus that was first isolated in the 1970s, and associated with Adult T-cell Leucemia-Lymphoma (ATLL), and subsequently to Tropical Spastic Paraparesis-Myelopathy (TSP/HAM). 29558516 2018
Entrez Id: 55729
Gene Symbol: ATF7IP
ATF7IP
0.050 Biomarker group BEFREE Studies suggest that IDH in children may be a marker for the development of T-cell leukemia/lymphoma (ATL) or myelopathy associated with HTLV-1/tropical spastic paraparesis (HAM / TSP) in adulthood. 28954118 2017
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.050 Biomarker group BEFREE Studies suggest that IDH in children may be a marker for the development of T-cell leukemia/lymphoma (ATL) or myelopathy associated with HTLV-1/tropical spastic paraparesis (HAM / TSP) in adulthood. 28954118 2017
Entrez Id: 55729
Gene Symbol: ATF7IP
ATF7IP
0.050 Biomarker group BEFREE Human T-cell Leukemia Virus type 1 (HTLV-1) is the etiological agent of tropical spastic paraparesis/HTLV-associated myelopathy (HAM/TSP) that can be identified in around 0.25%-3.8% of the infected population. 23510700 2013
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.050 Biomarker group BEFREE Human T-cell Leukemia Virus type 1 (HTLV-1) is the etiological agent of tropical spastic paraparesis/HTLV-associated myelopathy (HAM/TSP) that can be identified in around 0.25%-3.8% of the infected population. 23510700 2013
Entrez Id: 55729
Gene Symbol: ATF7IP
ATF7IP
0.050 GeneticVariation group BEFREE HTLV-1 infects millions of people around the world and induces myelopathy (HAM/TSP), adult T-cell leukemia (ATL) or other inflammatory or rheumatologic diseases. 20951636 2011
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.050 Biomarker group BEFREE HTLV-1 infects millions of people around the world and induces myelopathy (HAM/TSP), adult T-cell leukemia (ATL) or other inflammatory or rheumatologic diseases. 20951636 2011
Entrez Id: 55729
Gene Symbol: ATF7IP
ATF7IP
0.050 Biomarker group BEFREE Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in healthy virus carriers: application of best-fit logistic regression equation based on host genotype, age, and provirus load. 16877298 2006
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.050 Biomarker group BEFREE Clinical symptoms and the odds of human T-cell lymphotropic virus type 1-associated myelopathy/ tropical spastic paraparesis (HAM/TSP) in healthy virus carriers: application of best-fit logistic regression equation based on host genotype, age, and provirus load. 16877298 2006
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.030 Biomarker group BEFREE TNFα-I associated myelopathy should be considered in patients with history of treatment with TNFα-I who exhibit symptoms of myelopathy. 28131210 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.030 Biomarker group BEFREE Tumor necrosis factor, tumor necrosis factor receptors type 1 and 2, lymphotoxin-alpha, and HLA-DRB1 gene polymorphisms in human T-cell lymphotropic virus type I associated myelopathy. 11163081 2000
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.030 AlteredExpression group BEFREE Tumor necrosis factor alpha expression in the spinal cord of human T-cell lymphotrophic virus type I associated myelopathy/tropical spastic paraparesis patients. 8912208 1996
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
0.020 Biomarker group BEFREE We report a 49 year old male who presented with multiple sclerosis confirmed on brain MRI and CSF showing oligoclonal bands, with concomitant spinal myelopathy from a thoracic intradural extramedullary lesion. 31439491 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.020 GeneticVariation group BEFREE The ff genotype and f allele frequency of VDR-FokI were elevated in CSM patients. 30461062 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
0.020 GeneticVariation group BEFREE Role of APOE and IL18RAP gene polymorphisms in cervical spondylotic myelopathy in Indian population. 31126849 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.020 Biomarker group BEFREE We report a 49 year old male who presented with multiple sclerosis confirmed on brain MRI and CSF showing oligoclonal bands, with concomitant spinal myelopathy from a thoracic intradural extramedullary lesion. 31439491 2019
Entrez Id: 2638
Gene Symbol: GC
GC
0.020 GeneticVariation group BEFREE Association of VDR-FokI and VDBP-Thr420Lys polymorphisms with cervical spondylotic myelopathy: A case-control study in the population of China. 30461062 2019
Entrez Id: 2638
Gene Symbol: GC
GC
0.020 AlteredExpression group BEFREE Our study provides evidence that higher plasma VDBP, 25(OH)D, and GSH levels may predict better surgical outcome in CSM patients. 30848027 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.020 Biomarker group BEFREE The establishment of a definite diagnosis in TM requires a critical analysis of the MRI and CSF characteristics to rule out non-inflammatory causes of myelopathy. 29196574 2018
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
0.020 Biomarker group BEFREE The establishment of a definite diagnosis in TM requires a critical analysis of the MRI and CSF characteristics to rule out non-inflammatory causes of myelopathy. 29196574 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.020 Biomarker group BEFREE Local infusion of IL-6 led to myelopathy symptoms in model rats, which suggests that anti-inflammation can effectively treat DCM. 30327453 2018