Gene: ESR2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Therapeutic disease CTD_human "c-erbB-2 and the ""triple-state"" in early breast carcinomas." 19548127 2010
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease CTD_human "c-erbB-2 and the ""triple-state"" in early breast carcinomas." 19548127 2010
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta in the breast: role in estrogen responsiveness and development of breast cancer. 11162931 2000
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. 14729654 2004
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta and breast cancer. 15522549 2004
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer. 17009105 2007
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts. 17145865 2006
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor-beta: why may it influence clinical outcome in estrogen receptor-alpha positive breast cancer? 17617929 2007
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 AlteredExpression disease BEFREE Estrogen receptor-beta mRNA is associated with adverse outcome in patients with breast cancer. 19738412 2009
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 AlteredExpression disease BEFREE Estrogen receptor beta is overexpressed in around 70% breast cancer cases, referrd to as "ER positive". 20067880 2009
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 AlteredExpression disease BEFREE Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer. 20484043 2010
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE ERβ is considered to have a protective role in breast cancer development based on findings demonstrating that ERβ expression inhibits ERα-mediated proliferation of breast cancer cells. 21120602 2011
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE ERβ isoform 5 (ERβ5) has been positively correlated with better prognosis and longer survival of patients with breast cancer (BCa) in various clinical studies. 24339738 2013
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta-mediated proliferative inhibition and apoptosis in human breast cancer by calycosin and formononetin. 24355881 2013
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta as a novel target of androgen receptor action in breast cancer cell lines. 24552459 2014
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells. 28376210 2017
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor beta (ERβ) is endowed with oncosuppressive activities, antagonizing hormone-induced carcinogenesis and inhibiting growth and oncogenic functions in luminal-like breast cancers (BCs), where its expression correlates with a better prognosis of the disease. 29017520 2017
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Estrogen receptor β (ERβ) has recently been identified as a pharmaceutical target in hormone replacement therapy for breast cancers. 29610818 2018
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE ERβ alters the chemosensitivity of luminal breast cancer cells by regulating p53 function. 29854295 2018
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE ERβ protein was shown to be abundant in the majority of normal breast epithelial cells and is present in 20-30% of breast cancers. 31571071 2020
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE A great hallmark of breast cancer is the absence or presence of estrogen receptors ERα and ERβ, with a dominant role in cell proliferation, differentiation and cancer progression. 31401293 2020
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 AlteredExpression disease BEFREE A second estrogen receptor, ERβ, has been found to be expressed in 50% to 90% of ERα-negative breast cancers, and ERβ expression in TNBCs has been shown to correlate with improved disease-free survival and good prognosis. 23979844 2013
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE After adjusting for multiple-testing, our findings suggest that ESR2_CA is associated with breast cancer risk in Nigerian women, whereas ESR1_TA and AR_CAG seem to have no association with the disease among African American or Nigerian women. 22792352 2012
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 AlteredExpression disease BEFREE AKT regulation of estrogen receptor beta transcriptional activity in breast cancer. 16951146 2006
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.600 Biomarker disease BEFREE Altogether, this preliminary report indicates that the ERβ/RIP140 signaling is altered in unifocal breast cancers and correlated with patient outcome. 30669416 2019