| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | Biomarker | disease | BEFREE | The newly identified oncogenes RET/PTC1 and RET/PTC3 provide useful and specific markers of the early stages of papillary carcinoma as they are highly specific for malignant cells. | 9001272 | 1997 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | The present data do not support a major geographic difference in the prevalence of ret/PTC rearrangements in papillary carcinomas between Japan, the United States, and Italy. | 9669285 | 1998 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | The two rearrangements resulting from inversion of part of chromosome 10 (PTC1 and PTC3) accounted for the majority of RET rearrangements identified, with PTC1 being associated with papillary carcinomas of the classic and diffuse sclerosing variants and PTC3 with the solid/follicular variant. | 10646883 | 2000 | ||||
|
0.100 | Biomarker | disease | BEFREE | This study demonstrates that all thyroid carcinomas harboring activating RET rearrangements exhibit a well-differentiated phenotype, that of papillary carcinoma, and indicates that the subset of RET/PTC-positive papillary carcinomas do not progress to more aggressive, less differentiated tumor phenotypes. | 9516913 | 1998 | ||||
|
0.100 | Biomarker | disease | BEFREE | This study questions the relevance of PTC/retTPC oncogene in the carcinogenesis of thyroid papillary carcinomas in the Saudi population. | 8275421 | 1994 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | We analyzed the prevalence of BRAF point mutations and RET/PTC rearrangements in 55 post-Chernobyl papillary carcinomas, compared with 82 sporadic papillary carcinomas. | 15145515 | 2004 | ||||
|
0.100 | Biomarker | disease | BEFREE | We did not find any ret transcripts in papillary carcinomas negative for PTC activation, nor in normal thyroid and in non-papillary thyroid neoplasias. | 1457350 | 1992 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | We have recently reported the identification of a new oncogene, named PTC, frequently activated in human thyroid papillary carcinomas. | 1701232 | 1990 |