Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 Biomarker disease CTD_human
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 CausalMutation disease CLINVAR
Entrez Id: 215
Gene Symbol: ABCD1
ABCD1
0.010 Biomarker disease BEFREE CTS encodes a peroxisomal protein of the ATP binding cassette (ABC) transporter class with significant identity to the human X-linked adrenoleukodystrophy protein (ALDP). 12065405 2002
Entrez Id: 4973
Gene Symbol: OLR1
OLR1
0.010 AlteredExpression disease BEFREE CTS significantly attenuated atherosclerotic plaque formation and enhanced plaque stability in ApoE(-/-) mice by inhibiting the expression of lectin-like oxLDL receptor-1 (LOX-1) and MMP-9, as well as inhibiting reactive oxygen species (ROS) generation and NF-κB activation. 25572313 2015
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.010 AlteredExpression disease BEFREE CTS significantly attenuated atherosclerotic plaque formation and enhanced plaque stability in ApoE(-/-) mice by inhibiting the expression of lectin-like oxLDL receptor-1 (LOX-1) and MMP-9, as well as inhibiting reactive oxygen species (ROS) generation and NF-κB activation. 25572313 2015
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
0.010 AlteredExpression disease BEFREE CTS significantly attenuated atherosclerotic plaque formation and enhanced plaque stability in ApoE(-/-) mice by inhibiting the expression of lectin-like oxLDL receptor-1 (LOX-1) and MMP-9, as well as inhibiting reactive oxygen species (ROS) generation and NF-κB activation. 25572313 2015
Entrez Id: 268
Gene Symbol: AMH
AMH
0.010 Biomarker disease BEFREE Carpal tunnel was related to dialysis vintage and MIS. 31546847 2019
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 GeneticVariation disease BEFREE Transthyretin Tyr69-to-Ile mutation (double-nucleotide substitution in codon 69) in a Japanese familial amyloidosis patient with cardiomyopathy and carpal tunnel syndrome. 12762138 2003
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.010 GeneticVariation disease BEFREE Catechol-O-methyltransferase Val158Met polymorphism is associated with pain and disability, but not widespread pressure pain sensitivity, in women with carpal Tunnel syndrome. 24077209 2014
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
0.010 Biomarker disease BEFREE PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome. 29170419 2017
Entrez Id: 81794
Gene Symbol: ADAMTS10
ADAMTS10
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 4091
Gene Symbol: SMAD6
SMAD6
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 10866
Gene Symbol: HCP5
HCP5
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 165
Gene Symbol: AEBP1
AEBP1
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 23093
Gene Symbol: TTLL5
TTLL5
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 7372
Gene Symbol: UMPS
UMPS
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 4052
Gene Symbol: LTBP1
LTBP1
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 26
Gene Symbol: AOC1
AOC1
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 170691
Gene Symbol: ADAMTS17
ADAMTS17
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 2202
Gene Symbol: EFEMP1
EFEMP1
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome. 30833571 2019
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 GeneticVariation disease BEFREE A novel transthyretin Lys70Glu (p.Lys90Glu) mutation presenting with vitreous amyloidosis and carpal tunnel syndrome. 26828956 2016
Entrez Id: 5376
Gene Symbol: PMP22
PMP22
0.040 Biomarker disease BEFREE A review of the scientific literature indicated that neither the scientific basis nor the population validity of the PMP22 or TTR tests for carpal tunnel syndrome were adequately established before use on railroad track workers in 2000. 12802212 2003
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 Biomarker disease BEFREE A review of the scientific literature indicated that neither the scientific basis nor the population validity of the PMP22 or TTR tests for carpal tunnel syndrome were adequately established before use on railroad track workers in 2000. 12802212 2003
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 GeneticVariation disease LHGDN A Swedish family with the rare Phe33Leu transthyretin mutation. 16194875 2005
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.800 GeneticVariation disease BEFREE Although CTS associated with TTR amyloidosis has been known as an initial symptom in some patients with ATTR non-Val30Met FAP and those with senile systemic amyloidosis, this is the first report of ATTR Val30Met FAP patients starting with upper limb neuropathy including CTS-like symptoms. 20132088 2010