HLA-DQB1
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The highest HLA-DQB risk for CD development was found in patients carriers a DQ2.5/DQ8 genotype (1/10), followed by the patients carriers DQ2.5/DQ2.5 (1/12).
|
29793442 |
2018 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate a possible correlation between the HLA-DQA1 and HLA-DQB1 genetic markers and clinical features of celiac disease.
|
12050583 |
2002 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
CTD_human |
|
|
|
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
We studied nine consecutive DQ2-negative celiacs [from a group of 186 consecutive celiac disease (CD) patients] for the presence of the HLA-DQB1, DRB1, and DRBx alleles.
|
11061289 |
2000 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
HLA-DQA1 and HLA-DQB1 in Celiac disease predisposition: practical implications of the HLA molecular typing.
|
23050549 |
2012 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
However, multivariate analysis demonstrated that patients with potential CD have a higher frequency of both HLA-DQB1*0302 and HLA-DQB1*0603 alleles and a reduced frequency of DQB1*02 homozygosity compared with patients with uncomplicated and complicated CD.
|
21694611 |
2012 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
HPO |
|
|
|
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
LHGDN |
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease.
|
16878175 |
2006 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
The proportion of clinically undetected celiac disease may be particularly high among 3-year-old children with HLA-DQB1*02 and DQB1*0302 in Sweden, where these 2 HLA-risk alleles frequently occur.
|
19915493 |
2010 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
These results suggest that clinically suspected individuals for CD and first-degree relatives of patients with CD to be screened for HLA-DQB*0201 and DQB*0302 alleles for possible early diagnosis and treatments.
|
24917237 |
2014 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
LHGDN |
Gene, gut and schizophrenia: the meeting point for the gene-environment interaction in developing schizophrenia.
|
15617864 |
2005 |
HLA-DQB1
|
0.500 |
Biomarker
|
disease |
BEFREE |
The heterodimer HLA-DQB1*0201/-DQA1*0501, present in 96% of our patients, is strongly associated with CD susceptibility, confirming published reports.
|
8590546 |
1995 |