Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4 		0.010 GeneticVariation disease BEFREE Chronic sclerosing cholangitis was mimicked using the ATP-binding cassette transporter B4 knockout <i>(Abcb4</i> <sup>-/-</sup>) mouse model. 28194423 2017
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.320 Biomarker disease CTD_human Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model. 29808285 2018
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.320 Biomarker disease BEFREE Because MDR2 (rodent orthologue of human MDR3) knockout mice develop sclerosing cholangitis, it is attractive to speculate that MDR3 defects could also play an important role in cholangiopathies in humans. 17295178 2007
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.320 GeneticVariation disease BEFREE To generalize these observations, we suppressed β-catenin in Mdr2 knockout (KO) mice, which develop sclerosing cholangitis due to regurgitation of BA from leaky ducts. 31489648 2019
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4 		0.320 Biomarker disease CTD_human Multidrug resistance gene 2 knockout mice (Mdr2(-/-)) represent a well-characterized model for sclerosing cholangitis. 16472600 2006
Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8 		0.010 Biomarker disease BEFREE Complication-free survival did not differ between SC/IBD and SC patients, but survival was longer in patients without autoimmune features. 29316057 2018
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 109
Gene Symbol: ADCY3
ADCY3 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 79722
Gene Symbol: ANKRD55
ANKRD55 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 8853
Gene Symbol: ASAP2
ASAP2 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 9474
Gene Symbol: ATG5
ATG5 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		0.100 GeneticVariation disease GWASCAT Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. 27992413 2017
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		0.100 GeneticVariation disease GWASCAT Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. 23603763 2013
Entrez Id: 60468
Gene Symbol: BACH2
BACH2 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 55024
Gene Symbol: BANK1
BANK1 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 10018
Gene Symbol: BCL2L11
BCL2L11 		0.300 Biomarker disease CTD_human Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci. 21151127 2011
Entrez Id: 8927
Gene Symbol: BSN
BSN 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 339210
Gene Symbol: C17orf67
C17orf67 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 400757
Gene Symbol: C1orf141
C1orf141 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 64170
Gene Symbol: CARD9
CARD9 		0.100 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Entrez Id: 147372
Gene Symbol: CCBE1
CCBE1 		0.010 GeneticVariation disease BEFREE CCBE1 mutation causing sclerosing cholangitis: Expanding the spectrum of lymphedema-cholestasis syndrome. 28073151 2017