| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.700 | Biomarker | disease | CTD_human | A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. | 21946351 | 2011 | ||||
|
0.700 | Biomarker | disease | CTD_human | In patients with Dukes'C colorectal cancer who underwent curative surgical resection of the primary tumour, followed by 5-FU-based adjuvant chemotherapy, p53 mutation status as assessed by gene sequencing is a significant predictor of overall and metastasis-free survival. | 17949449 | 2008 | ||||
|
0.700 | Biomarker | disease | CTD_human | K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. | 18676755 | 2008 | ||||
|
0.700 | Biomarker | disease | CTD_human | Mutations that inactivate the transactivational ability of TP53 are more frequent in advanced CRC and are associated with worse prognosis in this stage of disease. | 16524972 | 2006 | ||||
|
0.700 | Biomarker | disease | CTD_human | Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients. | 16110022 | 2005 | ||||
|
0.700 | Biomarker | disease | CTD_human | Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer. | 15814641 | 2005 | ||||
|
0.700 | Biomarker | disease | CTD_human | Our data confirmed that p53 mutation is an independent pre-treatment factor in stage II and III colorectal cancer after curative resection. | 15172127 | 2004 | ||||
|
0.700 | Biomarker | disease | CTD_human | Correlation of Ki-67, p53, and Adnab-9 immunohistochemical staining and ploidy with clinical and histopathologic features of severely dysplastic colorectal adenomas. | 12645814 | 2003 | ||||
|
0.700 | Biomarker | disease | GENOMICS_ENGLAND |