Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.500 Biomarker disease CTD_human DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders. 29643356 2018
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
0.500 Biomarker disease MGD Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency. 23467366 2013
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
0.500 Biomarker disease MGD Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency. 18212115 2008
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.500 Biomarker disease MGD Behavioral phenotypes of Disc1 missense mutations in mice. 17481393 2007
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
0.500 Biomarker disease CTD_human Up-regulation of tryptophan hydroxylase-2 mRNA in the rat brain by chronic fluoxetine treatment correlates with its antidepressant effect. 17950541 2007
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.310 Biomarker disease BEFREE The following search items were used: "hypothalamic-pituitary-adrenal" OR "HPA" OR "cortisol" OR "corticotropin releasing hormone" OR "corticotropin releasing factor" OR "glucocorticoid*" OR "adrenocorticotropic hormone" OR "ACTH" AND "atypical depression" OR "non-atypical depression" OR "melancholic depression" OR "non-melancholic depression" OR "endogenous depression" OR "endogenomorphic depression" OR "non-endogenous depression". 29150144 2018
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 GeneticVariation disease BEFREE The following search items were used: "hypothalamic-pituitary-adrenal" OR "HPA" OR "cortisol" OR "corticotropin releasing hormone" OR "corticotropin releasing factor" OR "glucocorticoid*" OR "adrenocorticotropic hormone" OR "ACTH" AND "atypical depression" OR "non-atypical depression" OR "melancholic depression" OR "non-melancholic depression" OR "endogenous depression" OR "endogenomorphic depression" OR "non-endogenous depression". 29150144 2018
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.310 Biomarker disease CTD_human Continuous expression of corticotropin-releasing factor in the central nucleus of the amygdala emulates the dysregulation of the stress and reproductive axes. 18698320 2009
Entrez Id: 5443
Gene Symbol: POMC
POMC
0.310 Biomarker disease CTD_human Adrenocorticotropic hormone and cortisol plasma levels directly correlate with childhood neglect and depression measures in addicted patients. 18201294 2008
Entrez Id: 1392
Gene Symbol: CRH
CRH
0.310 Biomarker disease CTD_human Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates. 12438692 2002
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 7038
Gene Symbol: TG
TG
0.300 Biomarker disease CTD_human Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice. 30373627 2018
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
0.300 Biomarker disease CTD_human Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses. 26860412 2017
Entrez Id: 6403
Gene Symbol: SELP
SELP
0.300 Biomarker disease CTD_human Platelet hyperactivity, neurobehavioral symptoms and depression among Indian women chronically exposed to low level of arsenic. 25451969 2014
Entrez Id: 6281
Gene Symbol: S100A10
S100A10
0.300 Biomarker disease CTD_human Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. 21682946 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Therapeutic disease CTD_human Increased expression of the Vesicular Glutamate Transporter-1 (VGLUT1) in the prefrontal cortex correlates with differential vulnerability to chronic stress in various mouse strains: effects of fluoxetine and MK-801. 21945287 2012
Entrez Id: 23705
Gene Symbol: CADM1
CADM1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 2739
Gene Symbol: GLO1
GLO1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 2782
Gene Symbol: GNB1
GNB1
0.300 Biomarker disease CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448 2012
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.300 Biomarker disease CTD_human Estradiol and progesterone modify the effects of the serotonin reuptake transporter polymorphism on serotonergic responsivity to citalopram. 21843009 2011
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
0.300 Biomarker disease CTD_human 5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques. 21871532 2011
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.300 Biomarker disease CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 10016
Gene Symbol: PDCD6
PDCD6
0.300 Biomarker disease PSYGENET Gene expression in patients with endogenous depression was similar to that in the normal controls, except for upregulation of five genes (APP, CREBBP, GNAS, PDCD2 and PDCD6). 19955554 2010