Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
0.300 Biomarker disease CTD_human Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. 12973667 2003
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
0.300 Biomarker disease CTD_human Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. 14508707 2003
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
0.010 GeneticVariation disease BEFREE There is evidence that polymorphisms of CYP2C9 and the use of PHT are associated with an increase in the frequency of some side effects, such as cerebellar atrophy, gingival hypertrophy or acute cutaneous reactions. 29636628 2018
Entrez Id: 10631
Gene Symbol: POSTN
POSTN
0.010 AlteredExpression disease BEFREE We have previously demonstrated that periostin, which is transforming growth factor-beta (TGF-β) inducible gene, is upregulated in various fibrotic conditions including gingival enlargement associated with nifedipine. 29916554 2018
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
0.010 Biomarker disease BEFREE Collectively, these findings support an important role of TRPA1 channels in phenytoin-induced GE, provide insight into the pathophysiologic mechanism, and offer novel therapeutic opportunities for its treatment. 28571526 2017
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.010 GeneticVariation disease BEFREE The aim of this study was to investigate whether an association exists between MMP-3 genotypes and gingival enlargement in kidney transplant patients medicated with cyclosporine A. 19778329 2010
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.010 GeneticVariation disease BEFREE The aim of the study was to determine whether there is an association between SPARC genotypes and gingival enlargement in kidney transplant patients given CsA. 17970686 2007
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
0.010 GeneticVariation disease BEFREE The aim of this study was to determine whether there is an association between genotypes of the MMP-1 gene and gingival enlargement in kidney transplant patients. 16945025 2006