| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.600 | GeneticVariation | disease | BEFREE | One of our E-GBM patients with initial gross total resection quickly recurred within 4 months, required a second resection, and then was placed on vemurafenib; she remains tumor free 21 months after second resection without neuroimaging evidence of residual disease, adding to the growing number of reports of successful treatment of BRAF-mutated glial tumors with drug. | 25581727 | 2015 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | The growth inhibitory effects of UAI-201 correlated with the BRAF-V600E genotype of the glioma cell lines. | 24721513 | 2014 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | We report a new IDH1 mutation associated with BRAF mutation in a very unusual glial tumor. | 24857351 | 2014 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | BRAF alterations are key in certain low-grade gliomas and pediatric gliomas but rarely in high-grade gliomas in adults. | 28271343 | 2017 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | The purpose of this study was to clarify the incidence of B-RAF mutations and their possible relation with tumor progression in a series of 82 human gliomas, including 49 astrocytic and 33 oligodendroglial tumors. | 15791479 | 2005 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | The BRAF mutation V600E is critical to the pathogenesis of 10-20% of pediatric gliomas, and a small proportion of adult HGGs. | 26384810 | 2016 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | Our data indicate that BRAF(V600E) is a common genetic alteration in low-grade glial tumors with neuronal component or differentiation. | 25346165 | 2015 | ||||
|
0.600 | GeneticVariation | disease | BEFREE | CDKN2A, and PTEN in high-grade gliomas, followed by BRAF fusions in low-grade gliomas and H3F3A mutations in pediatric gliomas. | 26681766 | 2016 | ||||
|
0.600 | CausalMutation | disease | CGI |