Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5593
Gene Symbol: PRKG2
PRKG2 		0.010 Biomarker disease BEFREE This study suggests that the cGK II gene on chromosome 4q21 is most likely to harbour gout disease independently of hyperuricaemia and is inherited recessively. 18678579 2009
Entrez Id: 6280
Gene Symbol: S100A9
S100A9 		0.010 AlteredExpression disease BEFREE MRP-8/MRP-14 was measured in paired serum and synovial fluid samples by enzyme-linked immunosorbent assay (ELISA) and localized in synovial tissue from gout patients by immunohistochemistry. 24470119 2014
Entrez Id: 6885
Gene Symbol: MAP3K7
MAP3K7 		0.010 Biomarker disease BEFREE The expression levels of total TAK1 and phosphorylated TAK1 in gout patients were detected by western blotting. 30537632 2019
Entrez Id: 7182
Gene Symbol: NR2C2
NR2C2 		0.010 Biomarker disease BEFREE The expression levels of total TAK1 and phosphorylated TAK1 in gout patients were detected by western blotting. 30537632 2019
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.010 GeneticVariation disease BEFREE Lack of association of -607 C/A and -137 G/C polymorphisms in interleukin 18 gene with susceptibility to gout disease in Chinese Han male population. 21487696 2012
Entrez Id: 30061
Gene Symbol: SLC40A1
SLC40A1 		0.010 Biomarker disease BEFREE Surgical amputation of the gout lesion at MTP1 maximized the function, and reduced the pain of this patient. 29069047 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.010 AlteredExpression disease BEFREE Synovial T cells from rheumatoid arthritis and gout patients could be rescued from spontaneous apoptosis in vitro either by IL-2R gamma chain signaling cytokines (which upregulate Bcl-2 and Bcl-XL) or by interaction with synovial fibroblasts (which upregulates Bcl-xL but not Bcl-2). 9022077 1997
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.010 Biomarker disease BEFREE Cost-effectiveness analysis of genotyping for HLA-B*5801 and an enhanced safety program in gout patients starting allopurinol in Singapore. 26554739 2015
Entrez Id: 7369
Gene Symbol: UMOD
UMOD 		0.100 GeneticVariation disease CLINVAR
Entrez Id: 55157
Gene Symbol: DARS2
DARS2 		0.100 CausalMutation disease CLINVAR
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 Biomarker disease CTD_human Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528 2019
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 Biomarker disease CTD_human Analysis of the effect of the bovine adenosine triphosphate-binding cassette transporter G2 single nucleotide polymorphism Y581S on transcellular transport of veterinary drugs using new cell culture models. 21821808 2011
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 Biomarker disease CTD_human SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. 18327256 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 Biomarker disease CTD_human SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. 18327257 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.310 Biomarker disease CTD_human Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout. 26462562 2015
Entrez Id: 929
Gene Symbol: CD14
CD14 		0.310 Biomarker disease CTD_human Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout. 26462562 2015
Entrez Id: 126133
Gene Symbol: ALDH16A1
ALDH16A1 		0.300 Biomarker disease CTD_human Identification of low-frequency variants associated with gout and serum uric acid levels. 21983786 2011
Entrez Id: 80216
Gene Symbol: ALPK1
ALPK1 		0.300 Biomarker disease CTD_human Enhanced alpha-kinase 1 accelerates multiple early nephropathies in streptozotocin-induced hyperglycemic mice. 27542954 2016
Entrez Id: 7498
Gene Symbol: XDH
XDH 		0.300 Biomarker disease CTD_human Potential cow milk xanthine oxidase inhibitory and antioxidant activity of selected phenolic acid derivatives. 29071757 2018
Entrez Id: 22900
Gene Symbol: CARD8
CARD8 		0.300 Biomarker disease CTD_human Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout. 26462562 2015
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Therapeutic disease CTD_human Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. 18403674 2008
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASCAT Integrative Genome-Wide Association Studies of eQTL and GWAS Data for Gout Disease Susceptibility. 30899057 2019
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASCAT Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response. 25676789 2015
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASCAT Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. 23263486 2013
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASCAT Identification of low-frequency variants associated with gout and serum uric acid levels. 21983786 2011