Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3251
Gene Symbol: HPRT1
HPRT1 		0.130 GeneticVariation disease LHGDN HPRTSardinia: a new point mutation causing HPRT deficiency without Lesch-Nyhan disease. 16216473 2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		0.020 Biomarker disease BEFREE The plasma concentrations of IL-18, IL-6, and IL-8 were elevated in the presence of gouty arthritis in the gout patients. 16406656 2006
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASDB The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. 17997608 2007
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.010 GeneticVariation disease BEFREE Furthermore, the IL-4 (promoter-590 and intron 3) and TNF-alpha genotypes were not found to be associated with the clinical and laboratory profiles in gout patients. 17631734 2007
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.010 GeneticVariation disease BEFREE Furthermore, the IL-4 (promoter-590 and intron 3) and TNF-alpha genotypes were not found to be associated with the clinical and laboratory profiles in gout patients. 17631734 2007
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASDB Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. 18834626 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 Biomarker disease CTD_human SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. 18327256 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASDB SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. 18327257 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASDB Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. 18834626 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 Biomarker disease CTD_human SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. 18327257 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASDB Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. 18179892 2008
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASDB SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. 18327256 2008
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		0.300 Therapeutic disease CTD_human Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. 18403674 2008
Entrez Id: 10786
Gene Symbol: SLC17A3
SLC17A3 		0.100 GeneticVariation disease GWASDB Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. 18834626 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.010 GeneticVariation disease BEFREE The polymorphism 869T/C in TGF-beta1 gene has a significant association with the occurrence of tophus in gout patients. 18356176 2008
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease BEFREE Furthermore, 10% of gout patients (16 out of 159 cases) had genotype combinations resulting in more than 75% reduction of ABCG2 function (odds ratio, 25.8). 20368174 2009
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.010 AlteredExpression disease BEFREE In the present study, we determined whether benzbromarone increases the serum level of adiponectin in gout patients and investigated the mechanism involved. 19048458 2009
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.010 GeneticVariation disease BEFREE Neither the polymorphisms -572C/G nor -373A(m)T(n) in the genotype or allele distributions showed a significant association related to clinical characteristics, biochemical markers, IL-6 levels or gout disease (all p>0.05). 19032817 2009
Entrez Id: 5593
Gene Symbol: PRKG2
PRKG2 		0.010 Biomarker disease BEFREE This study suggests that the cGK II gene on chromosome 4q21 is most likely to harbour gout disease independently of hyperuricaemia and is inherited recessively. 18678579 2009
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASDB Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.450 GeneticVariation disease GWASCAT Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASDB Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010
Entrez Id: 56606
Gene Symbol: SLC2A9
SLC2A9 		0.400 GeneticVariation disease GWASCAT Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010
Entrez Id: 85460
Gene Symbol: ZNF518B
ZNF518B 		0.110 GeneticVariation disease GWASDB Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010
Entrez Id: 9379
Gene Symbol: NRXN2
NRXN2 		0.100 GeneticVariation disease GWASDB Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. 20884846 2010