Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 646702
Gene Symbol: HLA-DPA2
HLA-DPA2 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies two new risk loci for Graves' disease. 21841780 2011
Entrez Id: 7936
Gene Symbol: NELFE
NELFE 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 1589
Gene Symbol: CYP21A2
CYP21A2 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 7919
Gene Symbol: DDX39B
DDX39B 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 4026
Gene Symbol: LPP
LPP 		0.100 GeneticVariation disease GWASDB Seven newly identified loci for autoimmune thyroid disease. 22922229 2012
Entrez Id: 6941
Gene Symbol: TCF19
TCF19 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 11116
Gene Symbol: FGFR1OP
FGFR1OP 		0.100 GeneticVariation disease GWASDB Seven newly identified loci for autoimmune thyroid disease. 22922229 2012
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1 		0.100 GeneticVariation disease GWASDB Seven newly identified loci for autoimmune thyroid disease. 22922229 2012
Entrez Id: 3137
Gene Symbol: HLA-J
HLA-J 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 11116
Gene Symbol: FGFR1OP
FGFR1OP 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies two new risk loci for Graves' disease. 21841780 2011
Entrez Id: 4340
Gene Symbol: MOG
MOG 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 3132
Gene Symbol: HLA-DRB9
HLA-DRB9 		0.100 GeneticVariation disease GWASDB A genome-wide association study identifies two new risk loci for Graves' disease. 21841780 2011
Entrez Id: 101929163
Gene Symbol: TSBP1-AS1
TSBP1-AS1 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 10665
Gene Symbol: TSBP1
TSBP1 		0.100 GeneticVariation disease GWASDB Identification of independent risk loci for Graves' disease within the MHC in the Japanese population. 21900946 2011
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3 		0.110 Biomarker disease HPO
Entrez Id: 100134444
Gene Symbol: KCNJ18
KCNJ18 		0.100 Biomarker disease HPO
Entrez Id: 779
Gene Symbol: CACNA1S
CACNA1S 		0.100 Biomarker disease HPO
Entrez Id: 1188
Gene Symbol: CLCNKB
CLCNKB 		0.100 Biomarker disease HPO
Entrez Id: 2556
Gene Symbol: GABRA3
GABRA3 		0.100 Biomarker disease HPO
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.500 Biomarker disease LHGDN Here we use a new adenovirus-mediated animal model of Graves disease to show that goiter and hyperthyroidism occur to a much greater extent when the adenovirus expresses the free A subunit as opposed to a genetically modified TSHR that cleaves minimally into subunits. 12813025 2003
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.500 Biomarker disease LHGDN These results indicated that GD patients have an expanded Th2 population responding to TSH-R and the dominance of the humoral immune system in such patients. 11814624 2002
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.500 AlteredExpression disease LHGDN Adipose thyrotrophin receptor expression is elevated in Graves' and thyroid eye diseases ex vivo and indicates adipogenesis in progress in vivo. 12790806 2003
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		0.500 Biomarker disease LHGDN Association of PTPN22 haplotypes with Graves' disease. 17148556 2007
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.400 GeneticVariation disease LHGDN In this study, associations of five CTLA4 single nucleotide polymorphisms (-1722A/G, -1661A/G, -318C/T, +49G/A, CT60) with GD risk and GO susceptibility in GD patients were investigated in a Chinese population. 16893393 2006
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.400 GeneticVariation disease LHGDN We also found the HLA-DRB1*03 allele to be associated with GD; interestingly, the association of the CTLA-4 markers was independent from the HLA DRB1*03 status. 15785242 2005