×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.700
Biomarker
group
CTD_human
TLR4/MyD88/NF-κB signaling and PPAR-γ within the paraventricular nucleus are involved in the effects of telmisartan in hypertension.
27292124
2016
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.700
Therapeutic
group
CTD_human
TLR4/MyD88/NF-κB signaling and PPAR-γ within the paraventricular nucleus are involved in the effects of telmisartan in hypertension.
27292124
2016
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.700
Biomarker
group
CTD_human
A custom rat and baboon hypertension gene array to compare experimental models.
22228705
2012
×
Entrez Id:
348
Gene Symbol:
APOE
APOE
0.700
Biomarker
group
CTD_human
Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas.
20720404
2010
×
Entrez Id:
2908
Gene Symbol:
NR3C1
NR3C1
0.700
Biomarker
group
CTD_human
The glucocorticoid receptor is required for experimental adrenocorticotrophic hormone-induced hypertension in mice.
20659135
2010
×
Entrez Id:
4313
Gene Symbol:
MMP2
MMP2
0.700
Biomarker
group
CTD_human
Many recent studies have shown the involvement of matrix metalloproteinases (MMPs) in hypertension , particularly MMP-2 .
18836702
2009
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Biomarker
group
CTD_human
These data highlight the potential utility of eNOS gene therapy in the treatment of hypertension and insulin resistance.
19008412
2009
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Therapeutic
group
CTD_human
These data highlight the potential utility of eNOS gene therapy in the treatment of hypertension and insulin resistance.
19008412
2009
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.700
Biomarker
group
CTD_human
Our findings suggest that PPAR-gamma may be a key regulator of blood-brain barrier permeability and a potential therapeutic target during hypertension .
19666838
2009
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Biomarker
group
CTD_human
Genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure, and cardiovascular events in hypertension .
19407804
2009
×
Entrez Id:
490
Gene Symbol:
ATP2B1
ATP2B1
0.700
Biomarker
group
CTD_human
Genome-wide association study of blood pressure and hypertension.
19430479
2009
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Therapeutic
group
CTD_human
Genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure, and cardiovascular events in hypertension .
19407804
2009
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.700
Therapeutic
group
CTD_human
Our findings suggest that PPAR-gamma may be a key regulator of blood-brain barrier permeability and a potential therapeutic target during hypertension .
19666838
2009
×
Entrez Id:
2908
Gene Symbol:
NR3C1
NR3C1
0.700
Biomarker
group
CTD_human
A critical role for vascular smooth muscle in acute glucocorticoid-induced hypertension.
18434569
2008
×
Entrez Id:
335
Gene Symbol:
APOA1
APOA1
0.700
Biomarker
group
CTD_human
Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine beta-synthase and apolipoprotein A-I .
18224302
2008
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Therapeutic
group
CTD_human
Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats.
16331104
2006
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Biomarker
group
CTD_human
Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats.
16331104
2006
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.700
Therapeutic
group
CTD_human
Three individuals with loss-of-function mutations of peroxisome proliferator-activated receptor gamma developed early hypertension .
15199296
2004
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.700
Biomarker
group
CTD_human
Three individuals with loss-of-function mutations of peroxisome proliferator-activated receptor gamma developed early hypertension .
15199296
2004
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Biomarker
group
CTD_human
Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice.
12947532
2003
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Therapeutic
group
CTD_human
Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice.
12947532
2003
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Biomarker
group
CTD_human
Insulin resistance in eNOS (-/-) mice was related specifically to impaired NO synthesis, because in equally hypertensive 1-kidney/1-clip mice (a model of renovascular hypertension ), insulin-stimulated glucose uptake was normal.
11457755
2001
×
Entrez Id:
4846
Gene Symbol:
NOS3
NOS3
0.700
Therapeutic
group
CTD_human
Insulin resistance in eNOS (-/-) mice was related specifically to impaired NO synthesis, because in equally hypertensive 1-kidney/1-clip mice (a model of renovascular hypertension ), insulin-stimulated glucose uptake was normal.
11457755
2001
×
Entrez Id:
3291
Gene Symbol:
HSD11B2
HSD11B2
0.700
Biomarker
group
CTD_human
Functional adrenocorticotropic hormone receptor in cultured human vascular endothelial cells : possible role in control of blood pressure.
11082157
2000
×
Entrez Id:
3291
Gene Symbol:
HSD11B2
HSD11B2
0.700
Biomarker
group
CTD_human
Recently, we have studied an unusual patient with mild low-renin hypertension and a homozygous mutation in the HSD11B2 gene.
9707624
1998