Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.270 | GeneticVariation | disease | BEFREE | These findings suggests that IGF-I (CA)(19) and IGFBP-3-202 A/C gene polymorphisms may be a risk factor for hypothyroidism. | 19064126 | 2009 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | Subsequent growth faltering is thought to be related to impairment of the GH/IGF-1 axis but children with T1DM are also more at risk of hypothyroidism and coeliac disease. | 12373017 | 2002 | ||||
|
0.270 | Biomarker | disease | BEFREE | Antibodies to TSHR and IGF-1R were present in animals challenged with hTSHR A-subunit plasmid, with predominantly TSH blocking antibodies and were profoundly hypothyroid. | 23900776 | 2013 | ||||
|
0.270 | Biomarker | disease | RGD | Serum IGF-I levels were reduced by approximately 30% in all the 18-day-old hypothyroid animals, and did not correlate with the duration of the hypothyroid state. | 1380443 | 1992 | ||||
|
0.270 | Biomarker | disease | BEFREE | During follow-up he manifested complications from the hydrocephalus and NDI including global developmental delay and growth failure with low IGF-1 and hypothyroidism. | 18553546 | 2008 | ||||
|
0.270 | Biomarker | disease | BEFREE | A positive correlation between insulin and IGF-I and a poor correlation between GH and IGF-I were found in both hypothyroid neonates (T and MMI-hypothyroid). | 9832414 | 1998 | ||||
|
0.270 | Biomarker | disease | BEFREE | Population specific data and influence of sub-clinical hypothyroidism on insulin like growth factor-1 (IGF-1) and its binding protein-3 (IGFBP-3) in Indian children is lacking. | 28672739 | 2017 | ||||
|
0.270 | AlteredExpression | disease | BEFREE | The most common endocrine abnormality was hypogonadism in 68%, followed by hyperprolactinemia (56%), hypothyroidism (54%), abnormal glucose metabolism (24%), adrenal insufficiency (17%), and high IGF-1 levels (15%). | 30239770 | 2019 |