Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.500 Biomarker disease CTD_human Investigation of delta-aminolevulinic acid dehydratase polymorphism affecting hematopoietic, hepatic and renal toxicity from lead in Han subjects of southwestern China. 24631795 2014
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.500 Biomarker disease CTD_human Lead concentration in plasma as a biomarker of exposure and risk, and modification of toxicity by δ-aminolevulinic acid dehydratase gene polymorphism. 23792432 2013
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.500 Biomarker disease CTD_human The difference in methylation frequencies between exposures and controls was statistically significant (p=0.002), and individuals with methylated ALAD gene showed an increased risk of lead poisoning (adjusted OR=3.57, 95% CI, 1.55-8.18). 21396434 2011
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.500 Biomarker disease RGD Oral supplementation of gossypin during lead exposure protects alteration in heme synthesis pathway and brain oxidative stress in rats. 19647414 2010
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.500 Biomarker disease RGD Changes in brain biogenic amines and haem biosynthesis and their response to combined administration of succimers and Centella asiatica in lead poisoned rats. 16597373 2006
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.310 Biomarker disease CTD_human [Association of vitamin D receptor gene haplotypes and genotype combinations with susceptibility to occupational elevated blood lead]. 23433214 2013
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.310 Biomarker disease CTD_human Vitamin D receptor haplotypes affect lead levels during pregnancy. 20692022 2010
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.310 GeneticVariation disease LHGDN The results also indicated that the individuals carrying the VDR B allele were more susceptible to lead poisoning. 14731356 2003
Entrez Id: 57510
Gene Symbol: XPO5
XPO5 		0.300 Biomarker disease CTD_human Association between Polymorphism of Exportin-5 and Susceptibility to Lead Poisoning in a Chinese Population. 28042866 2016
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		0.300 Biomarker disease CTD_human The relationship between XRCC3 gene polymorphism and susceptibility to lead poisoning in male lead-exposed workers was analyzed. 23803535 2013
Entrez Id: 3077
Gene Symbol: HFE
HFE 		0.300 Biomarker disease CTD_human HFE gene variants modify the association between maternal lead burden and infant birthweight: a prospective birth cohort study in Mexico City, Mexico. 20659343 2010
Entrez Id: 84560
Gene Symbol: MT4
MT4 		0.300 Biomarker disease CTD_human The association of metallothionein-4 gene polymorphism and renal function in long-term lead-exposed workers. 19921116 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.300 Biomarker disease CTD_human Matrix metalloproteinase-9 activity in plasma correlates with plasma and whole blood lead concentrations. 16700817 2006
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.200 Therapeutic disease RGD GSPE reduces lead-induced oxidative stress by activating the Nrf2 pathway and suppressing miR153 and GSK-3β in rat kidney. 28178683 2017
Entrez Id: 5860
Gene Symbol: QDPR
QDPR 		0.200 Biomarker disease RGD Effect of chronic lead exposure on biopterin metabolism in the rat neostriatum. 2359144 1990