Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | AlteredExpression | disease | BEFREE | The results of present study indicated that IFN-γ gene expression reduced in ALL patients. | 30443842 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | These results show for the first time in Mexicans, the relevant role that IFNG SNP has in the genetic etiology of ALL. | 30212785 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | A 4-year-old boy was diagnosed with standard-risk ALL and was receiving VDS (3 mg/m<sup>2</sup> ) for maintenance therapy and itraconazole for IFI recurrence. | 28782144 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | Patients included between May 2006 and October 2012 in the multicenter phase III trial for newly diagnosed ALL (GRAALL-2005) were retrospectively reviewed for the occurrence of IFI using the EORTC modified criteria. | 27397551 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | These results demonstrate that the influence of IFN-γ on ALL progression may not be mediated by selection of nascent transformed cells but rather through a general SOCS-mediated reduction in B-cell precursor proliferation. | 28295300 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | Moreover, significant increases in NK cell degranulation and enhancement of IFN-γ production against primary acute lymphoblastic leukemia and chronic lymphocytic leukemia targets were induced with reagent treatment of resting NK cells. | 23075808 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | We have shown that human mature t(9;22) acute lymphoblastic leukemia-derived (ALL) DCs induced autologous cytotoxic T cell responses and therefore asked whether t(9;22) ALL-DC secreted IFN-γ. | 20943267 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Likewise, the male-specific protective association of interferon-gamma (IFNG) SNP rs2069727 in MS was replicated with the same sex specificity in childhood ALL (OR = 0.6, 95% CI = 0.4-1.0, Mantel-Haenszel P = 0.03). | 21067287 | 2010 | ||||
|
0.090 | Biomarker | disease | BEFREE | Increased interferon gamma production by peripheral blood mononuclear cells in response to stimulation of overexpressed disease-specific 9-O-acetylated sialoglycoconjugates in children suffering from acute lymphoblastic leukaemia. | 15606547 | 2005 |