Gene: IDH2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients. 24606448 2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR [Mutation of isocitrate dehydrogenase 2 (IDH2) gene in Chinese AML patients and its clinical significance]. 23815907 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. 23558173 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Rapid detection of IDH2 (R140Q and R172K) mutations in acute myeloid leukemia. 23949315 2013
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR The role of mutations in epigenetic regulators in myeloid malignancies. 22898539 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. 22417203 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis. 22616558 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. 22397365 2012
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy. 21250968 2011
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR The prognostic significance of IDH2 mutations in AML depends on the location of the mutation. 21596855 2011
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR Impact of genetic features on treatment decisions in AML. 22160010 2011
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.700 CausalMutation disease CLINVAR IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders. 20946881 2010