Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 Biomarker disease CTD_human Copper-64-labeled anti-bcl-2 PNA-peptide conjugates selectively localize to bcl-2-positive tumors in mouse models of B-cell lymphoma. 26239085 2015
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 GeneticVariation disease BEFREE In this study, by using polymerase chain reaction and fluorescence in situ hybridization techniques, we have showed that there is neither t(14;18)/IGH-BCL2 nor IGH gene rearrangement in 4 de novo IDCS without a concurrent or known history of a B-cell lymphoma, including follicular lymphoma, indicating that BCL2 chromosomal translocation is not a general feature of de novo IDCS. 20736747 2010
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 AlteredExpression disease BEFREE Incidence of Epstein-Barr virus bcl-2 expression and chromosomal translocation t(14;18) in large cell lymphoma associated with paragranuloma (lymphocyte-predominant Hodgkin's disease). 8150454 1994
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 GeneticVariation disease BEFREE The difference of bcl-2 rearrangement frequency between follicular, mixed and large cell lymphoma was also statistically significant (P = 0.012). 8449825 1993
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 GeneticVariation disease BEFREE There was only one large-cell lymphoma with a bcl-2 rearrangement. 2200538 1990
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 GeneticVariation disease BEFREE bcl-2 and other genomic alterations in the prognosis of large-cell lymphoma. 2648153 1989
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.350 Biomarker disease CTD_human Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation. 3287162 1988
Entrez Id: 604
Gene Symbol: BCL6
BCL6
0.320 Biomarker disease CTD_human Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6. 25543051 2015
Entrez Id: 604
Gene Symbol: BCL6
BCL6
0.320 AlteredExpression disease BEFREE In the presence of EBV infection, BCL-6 expressing AIDS-LCL fails to express the latent membrane protein 1 (LMP1) antigen. 12055673 2002
Entrez Id: 604
Gene Symbol: BCL6
BCL6
0.320 GeneticVariation disease BEFREE This study suggests that BCL6 rearrangement is primarily associated with large cell lymphoma, and that BCL2(-)BCL6(+) NHL could potentially be curable with modern combination chemotherapy. 9209377 1997
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
0.300 Biomarker disease CTD_human Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma. 26506619 2015
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.300 Biomarker disease CTD_human Variation in effects of non-Hodgkin lymphoma risk factors according to the human leukocyte antigen (HLA)-DRB1*01:01 allele and ancestral haplotype 8.1. 22096508 2011
Entrez Id: 6470
Gene Symbol: SHMT1
SHMT1
0.300 Biomarker disease CTD_human Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study. 17119116 2007
Entrez Id: 875
Gene Symbol: CBS
CBS
0.300 Biomarker disease CTD_human Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study. 17119116 2007
Entrez Id: 2356
Gene Symbol: FPGS
FPGS
0.300 Biomarker disease CTD_human Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study. 17119116 2007
Entrez Id: 635
Gene Symbol: BHMT
BHMT
0.300 Biomarker disease CTD_human Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study. 17119116 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.300 Biomarker disease CTD_human Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival. 17488658 2007
Entrez Id: 7037
Gene Symbol: TFRC
TFRC
0.300 Biomarker disease CTD_human The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer. 16904380 2006
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
0.300 Biomarker disease CTD_human Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes. 16365025 2005
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
0.300 Therapeutic disease CTD_human High dose cyclophosphamide plus recombinant human granulocyte-colony stimulating factor (rhG-CSF) in the treatment of follicular, low grade non-Hodgkin's lymphoma: CALGB 9150. 11911406 2002
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
0.300 Biomarker disease CTD_human Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas. 11406608 2001
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.300 Therapeutic disease CTD_human DICE (dexamethasone, ifosfamide, cisplatin, etoposide) infusional chemotherapy for refractory or relapsed non-Hodgkin's lymphoma (NHL). 11486401 2001
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.300 Therapeutic disease CTD_human Full-dose CHOP chemotherapy combined with granulocyte colony-stimulating factor for aggressive non-Hodgkin's lymphoma in elderly patients: a prospective study. 11732872 2001
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
0.300 Biomarker disease CTD_human Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas. 11406608 2001
Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
0.300 Therapeutic disease CTD_human Intensive conventional-dose chemotherapy for stage IV low-grade lymphoma: high remission rates and reversion to negative of peripheral blood bcl-2 rearrangement. 7515650 1994