Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.200 ModifyingMutation disease RGD This study was designed to investigate the expression differences of insulin-like growth factor-1 (IGF1), IGF type 1 receptor (IGFR1) and IGF-binding protein-3 (IGFBP3) in mandibular condylar cartilage between male and female rats with experimentally created malocclusion. 22758598 2012
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.200 Biomarker disease RGD Differential expression of IGF1, IGFR1 and IGFBP3 in mandibular condylar cartilage between male and female rats applied with malocclusion. 22758598 2012
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.200 Biomarker disease RGD Differential expression of IGF1, IGFR1 and IGFBP3 in mandibular condylar cartilage between male and female rats applied with malocclusion. 22758598 2012
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
0.200 Biomarker disease RGD Occlusal disharmony increases amyloid-β in the rat hippocampus. 21751079 2011
Entrez Id: 2736
Gene Symbol: GLI2
GLI2
0.110 GeneticVariation disease BEFREE The present study suggests that SNPs in TA-associated GLI2 and GLI3 genes may also play a role in the development of skeletal malocclusions. rs3738880 and rs2278741 in GLI2 seems to contribute to the genetic background for skeletal Class III and TA, respectively. 31112935 2019
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.110 Biomarker disease BEFREE Sequence analysis of COL1A1/COL1A2 and other OI-related genes was compared to the Peer Assessment Rating (PAR), an index reflecting the severity of malocclusion. 29388328 2018
Entrez Id: 2736
Gene Symbol: GLI2
GLI2
0.110 Biomarker disease HPO
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
0.110 Biomarker disease HPO
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
0.100 Biomarker disease HPO
Entrez Id: 1009
Gene Symbol: CDH11
CDH11
0.100 Biomarker disease HPO
Entrez Id: 2074
Gene Symbol: ERCC6
ERCC6
0.100 Biomarker disease HPO
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
0.100 Biomarker disease HPO
Entrez Id: 1289
Gene Symbol: COL5A1
COL5A1
0.100 Biomarker disease HPO
Entrez Id: 9411
Gene Symbol: ARHGAP29
ARHGAP29
0.100 Biomarker disease HPO
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
0.100 Biomarker disease HPO
Entrez Id: 80144
Gene Symbol: FRAS1
FRAS1
0.100 Biomarker disease HPO
Entrez Id: 4487
Gene Symbol: MSX1
MSX1
0.100 Biomarker disease HPO
Entrez Id: 8626
Gene Symbol: TP63
TP63
0.100 Biomarker disease HPO
Entrez Id: 6497
Gene Symbol: SKI
SKI
0.100 Biomarker disease HPO
Entrez Id: 51109
Gene Symbol: RDH11
RDH11
0.100 Biomarker disease HPO
Entrez Id: 6197
Gene Symbol: RPS6KA3
RPS6KA3
0.100 Biomarker disease HPO
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
0.100 Biomarker disease HPO
Entrez Id: 85358
Gene Symbol: SHANK3
SHANK3
0.100 Biomarker disease HPO
Entrez Id: 1855
Gene Symbol: DVL1
DVL1
0.100 Biomarker disease HPO
Entrez Id: 1739
Gene Symbol: DLG1
DLG1
0.100 Biomarker disease HPO