Gene: HLA-DRB5 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.100 GeneticVariation disease BEFREE These results confirm the proposed positive association of the Dw2 (DRB1*1501 DQA1*0102 DQB1*0602) haplotype with MS in Caucasians in our Turkish population (25 vs. 8, p = 0.003, OR = 3.7). 9328791 1997
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.100 GeneticVariation disease BEFREE This indicates that the Dw2 haplotype, when present in familial MS, may confer a stronger influence in MS susceptibility than generally recognized. 8300862 1994
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.100 GeneticVariation disease BEFREE This observation supports the hypothesis that "normal" genes, common to all carriers of the DR15,DQ6,Dw2 haplotype, confer the increased genetic susceptibility to MS associated with this haplotype. 8093808 1993
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.100 Biomarker disease LHGDN Thus, HLA-DRB5 attenuates MS severity, a finding consistent with HLA-DRB5's proposed role as a modifier in experimental autoimmune encephalomyelitis. 18832704 2008
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.100 Biomarker disease BEFREE Thus, HLA-DRB5 attenuates MS severity, a finding consistent with HLA-DRB5's proposed role as a modifier in experimental autoimmune encephalomyelitis. 18832704 2008
Entrez Id: 3127
Gene Symbol: HLA-DRB5
HLA-DRB5 		0.100 Biomarker disease BEFREE We used an extremes-of-outcome design with 48 benign and 20 malignant MS patients to assess whether or not DNA methylation at HLA-DRB1*1501 and/or HLA-DRB5 also contributes to MS phenotypic heterogeneity. 20394989 2010