Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR De novo genic mutations among a Chinese autism spectrum disorder cohort. 27824329 2016
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Integrated analysis of whole-exome sequencing and transcriptome profiling in males with autism spectrum disorders. 25969726 2015
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Kelch proteins: emerging roles in skeletal muscle development and diseases. 24959344 2014
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Synaptic, transcriptional and chromatin genes disrupted in autism. 25363760 2014
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome). 24266877 2014
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. 24267886 2013
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR De novo mutations in histone-modifying genes in congenital heart disease. 23665959 2013
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Update on the Kelch-like (KLHL) gene family. 23676014 2013
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. 22495309 2012
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. 22266938 2012
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Rate of de novo mutations and the importance of father's age to disease risk. 22914163 2012
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR The cullin protein family. 21554755 2011
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Drosophila Kelch functions with Cullin-3 to organize the ring canal actin cytoskeleton. 20065088 2010
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Structural assembly of cullin-RING ubiquitin ligase complexes. 20880695 2010
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Gene expression alterations in cryptorchid males using spermatozoal microarray analysis. 18687424 2009
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR The cullin7 E3 ubiquitin ligase: a novel player in growth control. 18927510 2008
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors. 17559828 2007
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR The ubiquitin-proteasome system. 16595883 2006
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Cullin3 is a KLHL10-interacting protein preferentially expressed during late spermiogenesis. 16162871 2006
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Requirement of Cul3 for axonal arborization and dendritic elaboration in Drosophila mushroom body neurons. 15843622 2005
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice. 15136734 2004
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family. 15071497 2004
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Cullin-3 regulates pattern formation, external sensory organ development and cell survival during Drosophila development. 15511641 2004
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. 10500095 1999
Entrez Id: 8452
Gene Symbol: CUL3
CUL3
0.100 CausalMutation phenotype CLINVAR Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate. 3002982 1986