Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.500 Biomarker phenotype CTD_human Peroxynitrite induces HMGB1 release by cardiac cells in vitro and HMGB1 upregulation in the infarcted myocardium in vivo. 21113057 2011
Entrez Id: 841
Gene Symbol: CASP8
CASP8
0.500 Biomarker phenotype RGD Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury. 11934844 2002
Entrez Id: 847
Gene Symbol: CAT
CAT
0.500 Biomarker phenotype RGD Hyperbaric oxygenation pretreatment induces catalase and reduces infarct size in ischemic rat myocardium. 11510883 2001
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.500 Biomarker phenotype CTD_human Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. 12087064 2002
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1
0.500 Biomarker phenotype RGD Chronic intermittent hypoxia alters Ca2+ handling in rat cardiomyocytes by augmented Na+/Ca2+ exchange and ryanodine receptor activities in ischemia-reperfusion. 17267548 2007
Entrez Id: 6652
Gene Symbol: SORD
SORD
0.500 Biomarker phenotype RGD Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium. 14525943 2003
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype RGD Leupeptin preserves cardiac nitric oxide synthase 3 during reperfusion following long-term cardioplegia. 20828747 2010
Entrez Id: 842
Gene Symbol: CASP9
CASP9
0.500 Biomarker phenotype RGD Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury. 11934844 2002
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype RGD Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart. 18390819 2008
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.500 Biomarker phenotype CTD_human Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts. 15642760 2005
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker phenotype CTD_human Pharmacological preconditioning with resveratrol: an insight with iNOS knockout mice. 12003803 2002
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
0.500 Biomarker phenotype RGD Effects of landiolol on mechanical and metabolic changes in rat reperfused ischaemic hearts. 17201736 2007
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker phenotype CTD_human Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms. 14990356 2004
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.500 Biomarker phenotype CTD_human Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. 18549825 2008
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker phenotype RGD Donor simvastatin treatment abolishes rat cardiac allograft ischemia/reperfusion injury and chronic rejection through microvascular protection. 21844074 2011
Entrez Id: 581
Gene Symbol: BAX
BAX
0.500 Biomarker phenotype CTD_human Cardioprotective effects of benazepril, an angiotensin-converting enzyme inhibitor, in an ischaemia-reperfusion model of myocardial infarction in rats. 20026869 2009
Entrez Id: 574435
Gene Symbol: MIR376B
MIR376B
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 494324
Gene Symbol: MIR375
MIR375
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 574411
Gene Symbol: MIR451A
MIR451A
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 693167
Gene Symbol: MIR582
MIR582
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
0.300 Biomarker phenotype CTD_human Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit. 19207477 2009
Entrez Id: 574506
Gene Symbol: MIR503
MIR503
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 406957
Gene Symbol: MIR181C
MIR181C
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 406903
Gene Symbol: MIR10B
MIR10B
0.300 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012