Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 842
Gene Symbol: CASP9
CASP9
0.500 Therapeutic phenotype RGD Cardioprotection of tilianin ameliorates myocardial ischemia-reperfusion injury: Role of the apoptotic signaling pathway. 29538428 2018
Entrez Id: 840
Gene Symbol: CASP7
CASP7
0.500 Therapeutic phenotype RGD Cardioprotection of tilianin ameliorates myocardial ischemia-reperfusion injury: Role of the apoptotic signaling pathway. 29538428 2018
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.500 Therapeutic phenotype RGD Cardioprotection of tilianin ameliorates myocardial ischemia-reperfusion injury: Role of the apoptotic signaling pathway. 29538428 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Therapeutic phenotype RGD Cardioprotective effects of total flavonoids from Jinhe Yangxin prescription by activating the PI3K/Akt signaling pathway in myocardial ischemia injury. 29274587 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Therapeutic phenotype RGD Acute sleep deprivation preconditions the heart against ischemia/ reperfusion injury: the role of central GABA-A receptors. 29299201 2017
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
0.500 Therapeutic phenotype RGD The modified Yi qi decoction protects cardiac ischemia-reperfusion induced injury in rats. 28637456 2017
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
0.500 Therapeutic phenotype RGD [Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats]. 25547710 2014
Entrez Id: 581
Gene Symbol: BAX
BAX
0.500 Therapeutic phenotype RGD [Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats]. 25547710 2014
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.500 Therapeutic phenotype RGD Dobutamine-mediated heme oxygenase-1 induction via PI3K and p38 MAPK inhibits high mobility group box 1 protein release and attenuates rat myocardial ischemia/reperfusion injury in vivo. 23531454 2013
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.500 Biomarker phenotype CTD_human Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol. 22050707 2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.500 Biomarker phenotype RGD Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. 20851484 2011
Entrez Id: 5350
Gene Symbol: PLN
PLN
0.500 Therapeutic phenotype RGD Luteolin inhibits apoptosis and improves cardiomyocyte contractile function through the PI3K/Akt pathway in simulated ischemia/reperfusion. 21934351 2011
Entrez Id: 6403
Gene Symbol: SELP
SELP
0.500 Biomarker phenotype RGD Inhibition of semicarbazide-sensitive amine oxidase attenuates myocardial ischemia-reperfusion injury in an in vivo rat model. 21146547 2011
Entrez Id: 847
Gene Symbol: CAT
CAT
0.500 Therapeutic phenotype CTD_human The combined transduction of copper, zinc-superoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury. 21600015 2011
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.500 Biomarker phenotype CTD_human Peroxynitrite induces HMGB1 release by cardiac cells in vitro and HMGB1 upregulation in the infarcted myocardium in vivo. 21113057 2011
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker phenotype RGD Donor simvastatin treatment abolishes rat cardiac allograft ischemia/reperfusion injury and chronic rejection through microvascular protection. 21844074 2011
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.500 Therapeutic phenotype RGD Preconditioning with high mobility group box 1 protein protects against myocardial ischemia-reperfusion injury. 19540007 2010
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker phenotype CTD_human Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the advantage of resveratrol in diabetics with acute heart attack is antagonized by insulin. 20828608 2010
Entrez Id: 581
Gene Symbol: BAX
BAX
0.500 Therapeutic phenotype RGD [Effects of BNP preconditioning on myocardial cell apoptosis and expressions of bcl-2 and Bax during myocardial ischemia-reperfusion injury in rats]. 21223820 2010
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype RGD Leupeptin preserves cardiac nitric oxide synthase 3 during reperfusion following long-term cardioplegia. 20828747 2010
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.500 Therapeutic phenotype RGD [Protective effects of hypoxia-inducible factor-1 alpha on myocardial ischemia/reperfusion injury in rat and the role of protein kinase C in signal pathway]. 20170615 2010
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Therapeutic phenotype CTD_human Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the advantage of resveratrol in diabetics with acute heart attack is antagonized by insulin. 20828608 2010
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
0.500 Biomarker phenotype RGD Inhibition of endoplasm reticulum stress by ghrelin protects against ischemiareperfusion injury in rat heart. 19406177 2009
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.500 Biomarker phenotype RGD Hyperlipidemia does not prevent the cardioprotection by postconditioning against myocardial ischemia/reperfusion injury and the involvement of hypoxia inducible factor-1alpha upregulation. 19727523 2009
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker phenotype CTD_human Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit. 19207477 2009