Source: GWASCAT ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 246
Gene Symbol: ALOX15
ALOX15 		0.410 GeneticVariation disease GWASCAT Most notably, a missense variant in ALOX15 that causes a p.Thr560Met alteration in arachidonate 15-lipoxygenase (15-LO) confers large genome-wide significant protection against NP (P = 8.0 × 10<sup>-27</sup>, odds ratio = 0.32; 95% confidence interval = 0.26, 0.39) and CRS (P = 1.1 × 10<sup>-8</sup>, odds ratio = 0.64; 95% confidence interval = 0.55, 0.75). p.Thr560Met, carried by around 1 in 20 Europeans, was previously shown to cause near total loss of 15-LO enzymatic activity. 30643255 2019
Entrez Id: 2625
Gene Symbol: GATA3
GATA3 		0.130 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1 		0.120 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.110 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 29785
Gene Symbol: CYP2S1
CYP2S1 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 553103
Gene Symbol: MIR3936HG
MIR3936HG 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 60468
Gene Symbol: BACH2
BACH2 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 27086
Gene Symbol: FOXP1
FOXP1 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 8809
Gene Symbol: IL18R1
IL18R1 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 2879
Gene Symbol: GPX4
GPX4 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 745
Gene Symbol: MYRF
MYRF 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 746
Gene Symbol: TMEM258
TMEM258 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 9173
Gene Symbol: IL1RL1
IL1RL1 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4 		0.100 GeneticVariation disease GWASCAT A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis. 30643255 2019