Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7015
Gene Symbol: TERT
TERT 		0.500 Biomarker group CTD_human Genome-wide analysis of noncoding regulatory mutations in cancer. 25261935 2014
Entrez Id: 472
Gene Symbol: ATM
ATM 		0.500 Biomarker group CTD_human Prenatal exposure to flavonoids: implication for cancer risk. 21177254 2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.500 Biomarker group CTD_human Human ARF is implicated as a tumor suppressor gene, mainly in association with the simultaneous deletion of INK4A. 19223589 2009
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.500 Therapeutic group CTD_human Mutations of the breast cancer susceptibility gene 1 (BRCA1), a tumor suppressor, confer an increased risk for breast, ovarian, and prostate cancers. 15520196 2004
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.500 Biomarker group CTD_human Association of c-myc overexpression and hyperproliferation with arsenite-induced malignant transformation. 11559025 2001
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.500 Biomarker group CTD_human These data establish that p16Ink4a, along with p19Arf, functions as a tumour suppressor in mice. 11544531 2001
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R 		0.500 Biomarker group CTD_human c-fms is present in primary tumours as well as in their metastases in bone marrow. 1390197 1992
Entrez Id: 1869
Gene Symbol: E2F1
E2F1 		0.400 Biomarker group CTD_human Finally, we integrated this cooperative miRNA regulation into a more comprehensive network to account for E2F1-related chemoresistance in tumour cells. 29464002 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.400 Biomarker group CTD_human In agreement with this hypothesis, CRISPR-mediated deletion of SNORD50A and SNORD50B in KRAS-mutant tumor cells enhanced tumorigenesis, and SNORD50A and SNORD50B deletion and oncogenic KRAS mutation co-occurred significantly in multiple human tumor types. 26595770 2016
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B 		0.400 Biomarker group CTD_human An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. 26258849 2015
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		0.400 Biomarker group CTD_human Human health effects of dichloromethane: key findings and scientific issues. 25325283 2015
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2 		0.400 Biomarker group CTD_human Allogeneic transplantation of hERG1-expressing cells into nude mice resulted in an increased incidence of tumors. 24830940 2014
Entrez Id: 10232
Gene Symbol: MSLN
MSLN 		0.400 Biomarker group CTD_human Individual predictors of increased serum mesothelin in asbestos-exposed workers. 23277285 2013
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1 		0.400 Biomarker group CTD_human Excision repair of BPDE-adducts in human lymphocytes: diminished capacity associated with ERCC1 C8092A (rs3212986) polymorphism. 23203453 2013
Entrez Id: 3297
Gene Symbol: HSF1
HSF1 		0.400 Biomarker group CTD_human Thus, cancers of many histologies exhibit activated HSF1 and increased HSP levels that may help to deter tumor suppression and evade therapy in the clinic. 22885793 2013
Entrez Id: 1386
Gene Symbol: ATF2
ATF2 		0.400 Biomarker group CTD_human Oxidative stress and MAPK involved into ATF2 expression in immortalized human urothelial cells treated by arsenic. 23591579 2013
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R 		0.400 Biomarker group CTD_human The effects of GLP-1 agonists on C-cell proliferation or neoplasia have not been documented in nonhuman primates or humans. 23471186 2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.400 Biomarker group CTD_human Molecular characterization of a cancer-related single nucleotide polymorphism in the pro-inflammatory interleukin-1B gene. 22467534 2012
Entrez Id: 3606
Gene Symbol: IL18
IL18 		0.400 Therapeutic group CTD_human Investigation of PEG-PLGA-PEG nanoparticles-based multipolyplexes for IL-18 gene delivery. 21273262 2012
Entrez Id: 7528
Gene Symbol: YY1
YY1 		0.400 Biomarker group CTD_human Molecular characterization of a cancer-related single nucleotide polymorphism in the pro-inflammatory interleukin-1B gene. 22467534 2012
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR 		0.400 Biomarker group CTD_human Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells. 22261521 2012
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.400 Biomarker group CTD_human Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. 22037238 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.400 Biomarker group CTD_human P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation. 22269388 2012
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1 		0.400 Biomarker group CTD_human However, we previously reported that the absence of TRPV1 in mice results in a striking increase in skin carcinogenesis, suggesting that chronic blockade of TRPV1 might increase the risk of tumor development. 21349818 2011
Entrez Id: 2878
Gene Symbol: GPX3
GPX3 		0.400 Biomarker group CTD_human GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response. 21684681 2011